Mendelian Inheritance II Flashcards
when does inheritance of a single gene deviate from mendels laws
when ptypes of alleles are not completely dominant or recess
when a gene has > 2 alleles (multiple alleles)
when a gene produces multiple ptypes (pleiotropy)
incomplete dominance
offspring has intermediate ptype of parents
ex. white flower plus red flower = pink
codominance
both ptypes of each allele expressed
what is a disease that displays multiple layers of ptypes
Tay Sachs
at organismal level… tay sachs is
recessive
at the biochemical level, Tay Sachs is…
incompletely dominant
at molecular levle, Tay Sachs is
codominant
dominant human disorders
Huntingtons, achondroplasia, polydactyl
multiple alleles
ABO blood group
codominant ptype
pleiotropic
most genes
causes multiple ptypes
ex. sickle cell causes kidney and heart failure, paralysis, weakness and fatigue
define quantitative characters
vary along a continuum
indicates polygenic inheritance
polygenic inheritance
additive effect of 2 or more genes on a single ptype
many genes contributing to one ptype that is additive, ex. skin color
epistasis
gene at one locus changes ptypic expression of a gene at second locus
ex dog coat color…one gene is black or brown color other gene determines whether pigment will be deposited or not