Mendelian Inheritance II Flashcards

1
Q

when does inheritance of a single gene deviate from mendels laws

A

when ptypes of alleles are not completely dominant or recess
when a gene has > 2 alleles (multiple alleles)
when a gene produces multiple ptypes (pleiotropy)

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2
Q

incomplete dominance

A

offspring has intermediate ptype of parents

ex. white flower plus red flower = pink

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3
Q

codominance

A

both ptypes of each allele expressed

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4
Q

what is a disease that displays multiple layers of ptypes

A

Tay Sachs

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5
Q

at organismal level… tay sachs is

A

recessive

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6
Q

at the biochemical level, Tay Sachs is…

A

incompletely dominant

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7
Q

at molecular levle, Tay Sachs is

A

codominant

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8
Q

dominant human disorders

A

Huntingtons, achondroplasia, polydactyl

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9
Q

multiple alleles

A

ABO blood group

codominant ptype

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10
Q

pleiotropic

A

most genes
causes multiple ptypes
ex. sickle cell causes kidney and heart failure, paralysis, weakness and fatigue

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11
Q

define quantitative characters

A

vary along a continuum

indicates polygenic inheritance

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12
Q

polygenic inheritance

A

additive effect of 2 or more genes on a single ptype

many genes contributing to one ptype that is additive, ex. skin color

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13
Q

epistasis

A

gene at one locus changes ptypic expression of a gene at second locus
ex dog coat color…one gene is black or brown color other gene determines whether pigment will be deposited or not

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