Mendelian Inheritance

Question 1

What are the features of autosomal dominant inheritance?

Answer 1

Each generation is affected
Both sexes affected in equal proportion - equal transmission too 50%
Transmitted through infected individuals

Question 2

What are the features of autosomal recessive inheritance?

Answer 2

Affected individuals in a single generation
Generations are skipped
Both sexes are affected in equal proportion

Question 3

Give an example of a dominant autosomal disease

Answer 3

Achondroplasia 🧝‍♂️

Question 4

Why can a father never pass on an X linked condition to his son?

Answer 4

For a son to be born, he receives a Y paternal chromosome and a maternal X chromosome, for a female it’s x from dad x from mom 🧚🏽‍♀️

Question 5

Who can transmit an X related condition?

Answer 5

Unaffected women and affected men

Question 6

Can a female ever get haemophilia?

Answer 6

Yes, if she os the offspring of an affected male and a carrying mother