Memory Disorders Flashcards

1
Q

What is anterograde amnesia?

A

the inability to form new memories

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2
Q

What is retrograde amnesia?

A

memory loss from before the event

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3
Q

What is short term memory?

A

the ability to keep information online

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4
Q

What is working memory?

A

the ability to manipulate information in short term memory

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5
Q

What is long term memory?

A

storing information over minutes, hours and years

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6
Q

What is non declarative memory?

A

procedural memory e.g. how to ride a bike and priming/conditioning

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7
Q

What is declarative memory?

A

episodic memory e.g. events that relate to you as a person and semantic memory e.g. a banana is yellow

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8
Q

What brain structures are involved in declarative memory?

A

hippocampus, entorhinal cortex, perirhinal cortex

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9
Q

Is there any lateralisation of memory?

A

yes - left hippocampus predominantly for verbal memory and right hippocampus for non verbal memory

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10
Q

What are some degenerative causes of memory impairment?

A

alzheimers and chronic alcoholism (due mainly to the malnutrition)

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11
Q

What are some cerebrovascular causes of memory impairment?

A

bilateral thalamic infarction, cardiogenic cerebral anoxia

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12
Q

What are some transient causes of memory impairment?

A

transient global amnesia, temporal lobe epilepsy, post traumatic amnesia

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13
Q

What is the primary cause of memory impairment in temporal lobe epilepsy?

A

hippocampal sclerosis

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14
Q

What brain structures are involved in episodic memory?

A

mammillary bodies, medial temporal region, retrosplenial cortex, anterior thalamus, basal forebrain

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15
Q

What is transient global amnesia?

A

a sudden occurrence of a global dense anterograde amnesia out of the blue with no definite pathological correlate - sometimes with specific triggers such as emotional stress

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16
Q

What is post traumatic amnesia?

A

a period of time after a traumatic event when a person is unable to form reliable new memories - also involves behavioural symptoms including agitation, disturbance of sleep wake cycle, confusion

17
Q

What is mild cognitive impairment?

A

the transitional phase between normal ageing and dementia with mild memory impairment on objective assessment but activities of daily living and cognitive functioning are not affected

18
Q

In what areas of the brain are the neurofibrillary changes seen in the stages of alzheimers?

A

first the transentorhinal cortex is involved, then the entorhinal cortex, then the neocortical association cortex

19
Q

What language impairment is seen in alzheimer’s disease?

A

word finding difficulty