Learning and Memory

Question 1

What are some disorders involving deficiencies in learning and memory?

Answer 1

autism, ADD, down syndrome, depression, schizophrenia, addiction, alzheimers, dementia, huntington’s

Question 2

Where is memory stored?

Answer 2

medial temporal lobe

Question 3

What are the types of declarative memory?

Answer 3

semantic and episodic

Question 4

What are the types of non declarative memory?

Answer 4

skills and habits, priming, associative learning, non associative learning (reflexes)

Question 5

What is the cellular basis of learning and memory?

Answer 5

long term potentiation

Question 6

What receptors are involved in learning and memory?

Answer 6

NMDA and AMPA (glutamate receptors)

Question 7

Which is the result of up regulating the NR2B subunit of the NMDA receptor?

Answer 7

enhanced synaptic plasticity which leads to enhanced learning and memory

Question 8

What are the short term cellular changes in learning and memory?

Answer 8

insertion of AMPA receptors, phosphorylation of AMPA receptors, enhanced presynaptic release via retrograde signalling

Question 9

What are the long term cellular changes in learning and memory?

Answer 9

protein synthesis and structural changes