memory Flashcards

tommus (48 cards)

1
Q

What is memory?

A

A classification of memory through time; long-term memory lasts longer than 24 hours

Memory is still not fully understood, especially short-term memory.

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2
Q

What are the types of memory?

A
  • Sensory
  • Short-term memory
  • Long-term non-declarative
  • Long-term declarative

Long-term non-declarative memory influences behavior without conscious awareness.

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3
Q

What is semantic memory?

A

Information about the world, not your own experience

You may forget where you learned it.

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4
Q

Give an example of non-declarative memory.

A

Classical conditioning

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5
Q

Give an example of declarative memory.

A

Semantic memory

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6
Q

What is episodic memory?

A

Memory of personal experiences, events, and specific times/places

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7
Q

Where in the brain would non-declarative memory be found?

A
  • Basal ganglia
  • Cerebellum
  • Cortex
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8
Q

Where would declarative memory pathways be located?

A
  • Neocortex
  • Temporal lobe
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9
Q

What is procedural memory?

A

A type of long-term non-declarative memory that stores knowledge of how to perform tasks and motor skills

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10
Q

Describe the Atkinson and Shiffrin modal model of memory.

A

Information moves from sensory memory to short-term storage to long-term storage, with potential loss at any stage

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11
Q

What is the Baddeley and Hitch model?

A

Introduced the terms phonological loop and visuospatial sketchpad, with the Central Executive as the control center of working memory

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12
Q

What is the engram?

A

The hypothetical physical representation of a memory in the brain

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13
Q

Who was Henry Molaison (H.M.)?

A

A patient who had his hippocampus removed, leading to severe anterograde amnesia but intact short-term and procedural memory

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14
Q

What is the role of the hippocampus in memory?

A

Integrates and processes information before sending it back to the cortex for memory storage

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15
Q

What is the Morris Water Maze?

A

A test showing deficits in learning and memory in animals with hippocampal lesions

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16
Q

What is the plasticity mechanism?

A

Neurons strengthen and connect, allowing neural networks to reorganize by forming new connections

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17
Q

What is long-term depression (LTD)?

A

A long-lasting decrease in the strength of synaptic connections due to weak or infrequent activation

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18
Q

What is long-term potentiation (LTP)?

A

A process where repeated stimulation of one neuron leads to a long-lasting increase in the strength of synaptic transmission

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19
Q

What are the types of LTP receptors?

A
  • NMDA receptors
  • AMPA receptors
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20
Q

What is neuroplasticity?

A

The ability of the nervous system to be modified after birth

21
Q

What is memory consolidation?

A

The process of transforming short-term memories into long-term memories

22
Q

What is Anisomycin?

A

A protein synthesis blocker

23
Q

What does Hebb’s rule state?

A

Neurons that fire together wire together

24
Q

What is fear conditioning?

A

A process where a neutral stimulus becomes associated with a fearful event

25
What is the significance of channelrhodopsins in neuroscience?
They allow for the control of neuronal activity by shining light on them
26
What was Mark Mayford's contribution to memory research?
Investigated specific genes involved in memory processes using conditional knockout models
27
What is the construct of forgetting?
The brain's decision on what to forget, often perceived negatively by humans
28
What is emotion?
An involuntary response to stimuli
29
What are the dual aspects of emotion?
* Expression Behavioral * Physiological * Experience
30
How do we differentiate between emotion and mood?
* Emotion: Immediate responses to specific objects/situations * Mood: Long-lasting affective states with unclear origins
31
What are the neural systems of emotion?
* Corpus callosum * Orbitofrontal cortex * Hypothalamus * Amygdala * Cingulate gyrus * Thalamus * Hippocampus
32
What is Ekman's theory of emotion?
Proposes basic emotions that exhibit distinct universal signs
33
What are the broad categories of emotion?
* Basic Emotions * Complex Emotions * Dimensional Theories of Emotion
34
Describe patient S.M.
Had bilateral amygdala atrophy, leading to an inability to recognize fear
35
What are Darwin's principles of emotions?
* Principle of serviceable habits * Principle of antithesis * Principle of expressive habits
36
What is the emotion generation process?
* Physiological reaction * Behavioral reaction * Subjective feeling
37
What is the high road and low road approach in emotional responses?
The low road allows for faster emotional responses, while the high road involves cognitive interpretation
38
What does the Ochsner Cognitive Control Model describe?
How cognitive strategies regulate emotional responses through top-down control
39
What is the Amygdala anatomy?
* Major output region for emotional expression: central nucleus * Major sensory input region: lateral nucleus
40
What is classical conditioning?
A learning process where a neutral stimulus becomes associated with a significant stimulus
41
What are neurodegenerative disorders?
Diseases of brain degeneration, e.g., Alzheimer's Disease and Parkinson's Disease
42
What occurs in Alzheimer's disease?
Severe atrophy of cerebral hemispheres, loss of neurons, neurofibrillary tangles, and amyloid plaques
43
What is associated with Parkinson's disease?
Loss of dopamine-producing neurons in the substantia nigra
44
What are the positive and negative symptoms of schizophrenia?
* Positive: Delusions, hallucinations * Negative: Reduced speech, flattened effect
45
How can we study brain disorders?
* Clinical profile * Brain imaging * Behavioral assessment * Histology * Cell culture * Drug studies * Controlled interventions
46
What is the treatment for Parkinson's disease?
* L-DOPA * Deep Brain Stimulation * Stem Cell Therapies * Optogenetics
47
What is the role of Rho GTPase in intellectual disabilities?
Necessary for dendritic spine formation and normal behavior
48
How does SARS-CoV-2 affect brain cells?
Can infect neurons, leading to neurological symptoms like brain fog and cognitive decline