Membranes Flashcards
Semi-permeable layer that separates the cell from the external environment
Plasma membrane
Controls the passage of material into and out of the cell (gate keeper but does not protect)
Plasma membrane
Name the 5 components of cellular membranes.
- phospholipid bilayer
- cholesterol
- integral and peripheral proteins
- glycoproteins
- glycolipids
They form bi-layer framework
Phospholipids
It stabilizes phospholipid fluidity
Cholesterol
Bio-molecules found in membranes
- Lipid
- Protein
- Glyco-molecules (carbs)
What is glycolipid?
A complex of oligosaccharide bound to lipid used in tissue recognition
What is glycoprotein?
A complex of oligosaccharide bound to protein used in cell (“self”) recognition
Describes the membrane organization
Fluid mosaic model
Has AMPHIPATHIC properties (molecule is both polar and non-polar) which will influence what can cross the membrane
Phospholipid
Lipid bilayer
Plasma membrane
It has different effects on membrane fluidity at different temperatures
Cholesterol
At warm temperatures, it restrains movement of phospholipids
Cholesterol
At cool temperatures, it maintains fluidity by preventing tight packing
Cholesterol
Proteins that are embedded within the membrane
Integral Proteins
Proteins that are temporarily bound to surface of bilayer
Peripheral Proteins
Membrane protein functions (6)
- transporters: control movement of material
- enzymes: catalyze
- cell surface receptors: bind signal molecules
- cell surface identity markers: ID a cell type
- cell-to-cell adhesion proteins: bind cells
- attachments to the cytoskeleton: structure and guide
Active transport
Carrier, protein changes shape to move molecules, ATP needed (requires cellular energy)
Passive transport
Channel, selected ions (NA+) channels in heart, moves by diffusion (from high concentrartion to low), no energy needed
Special channel protein passively transports water
Aquaporin, osmosis
Determine shape of the cell
Spectrins
Anchor certain proteins to specific sites, especially on the exteriror plasma membrane in receptor-mediated endocytosis
Clathrins
Self recognition
Glycoproteins
Tissue recognition
Glycolipid
Bulk transport
Complex active mechanism
It is a response to a concentration gradient
Movement
Due to motion of bilayer: phospholipids slide along each other.
Fluid
Associated mix of molecules: globular proteins (cholesterol and glycolipids & glycoproteins).
Mosaic
Name transport proteins (3)
Carriers
Channels
Receptors