MEH thyroid

Question 1

What type of receptor does thyroid hormone bind to?

Answer 1

nuclear receptors

modulate gene expression. Thyroid hormone receptors can bind DNA in the absence of hormone, usually leading to transcriptional repression. Hormone binding is associated with a conformational change in the receptor that causes it to function as a transcriptional activator

Question 2

Goitre (enlargement of the thyroid gland) is associated with which?

Answer 2

both hyper and hypothyroidism

Question 3

Which form of thyroid hormone has the longest half-life?

Answer 3

T4

Question 4

effect of thyroid hormone?

Answer 4

stumulates an increase in both the number and size of mitochondria in cells.

Low levels of thyroid hormone stimulate glycogenesis

High levels of thyroid hormone stimulate glycogenolysis

Question 5

Which two of the following conditions are the most common causes of goitre?

Answer 5

Iodine deficiency

Multinodular goitre

Question 6

Which substance is produced by follicular cells in the thyroid gland?

Answer 6

thyroglobulin