MEH Steve revision morning Flashcards
precursor molecule of thyroid hormone?
tyrosine
precursor molecule of steroid hormones (aldosterone, progesterone, testosterone)
cholesterol
what happens to the capacity of urea cycle after a period of malnourishment?
decreases
down regulation of enzymes that control the urea cycle
ammonia toxicity happens - refeeding syndrome
what can happen with refeeding syndrome ?
hypophosphonaemia > drain on phosphate. pathways need phosphate to work.
urea cycle capacity decreases> ammonia toxicity
what drug is given for paracetamol overdose and depleted liver glutathione levels?
N-acetylcysteine (NAC)
erythrocytes with inclusions of DNA fragments are called?
Howell jolly bodies
seen in hypersplenism
denatured haemoglobin inclusion bodies are called?
Heinz bodies
what is hyperkinesis?
muscle spasms/ XS movement
what feature distinguishes between fatty acid oxidation and fatty acid synthesis in the liver?
fatty acid synthesis in the liver occurs in cytoplasm
fatty acid oxidation occurs in the mitochondria
synthesising fatty acids is cat/anabolic?
anabolic process
which hormone is not actually produced by pituitary gland despite being released by it?
ADH
oxytocin and ADH are the two hormones produced in hypothalamus then transported down axons to posterior pituitary for release there.
which medication can cause low haemoglobin (anaemia?)
asprin
long term use of NSAIDs potential side effect- chronic blood loss (GI bleeding) this can precipitate anaemia.
