Medicines in Respiratory Disease Flashcards

1
Q

how are respiratory drugs administered?

A
  • inhalation
  • oral
  • intravenous
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2
Q

how are topical drugs delivered to the lungs?

A
  • INHALATION

- delivers drug directly to the airway, not the circulation

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3
Q

what drugs are used to improve ventilation?

A

Improve airway patency:

  • bronchodilators
  • anti-inflammatory drugs

Prevent mast cell degranulation:

  • cromoglycate (mast cell stabilizer)
  • leukotriene receptor antagonists
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4
Q

what are examples of bronchodilators?

A
  • beta2 agonists
  • anticholinergic
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5
Q

what is an example of an anti-inflammatory drug?

A

corticosteroid

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6
Q

what drug can improve gas exchange?

A

OXYGEN

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7
Q

how are inhaled drugs delivered?

A
  • metered dose inhaler (MDI)
  • spinhaler
  • turbohaler
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8
Q

what can aid in inhaled drug delivery?

A
  • nebulisers
  • spacers
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9
Q

what is a nebuliser?

A

adevice that can deliver high doses of medicine quickly and easily. It works by changing liquid medicine into a fine mist.

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10
Q

what are examples of short-acting B2 agonists?

A
  • salbutamol
  • terbutaline
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11
Q

what drugs can be found in the blue inhaler?

A
  • salbutamol

- terbutaline

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12
Q

what is an example of a long-acting B2 agonist?

A
  • salmeterol
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13
Q

what drug is found in the green inhaler & why is it used?

A
  • salmeterol

- used to prevent an asthma attack

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14
Q

what is the function of anticholinergics?

A

they inhibit muscarinic nerve transmission in autonomic nerves (relaxation of smooth muscle)

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15
Q

what is the function of corticosteroids?

A

reduce inflammation in the bronchial walls (effective topically or systemically)

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16
Q

what is the function fo mast cell stabilisers and leukotriene inhibitors?

A

prevent release of chemical mediators in the bronchiole wall which initiate the process of asthma