Medication_Discontinuation syndrome

Question 1

antidepressant discontinuation syndrome

Answer 1

commonly seen after ceasing selective serotonin reuptake inhibitors → Sx occur 1/52 after ceasing te drg, resolves in 10/7
(Ref: Deprescribing 2015, NPS article)

Question 2

The abrupt withdrawal of benzodiazepines →

Answer 2

confusion, hallucinations and seizures.

Ref: Deprescribing 2015, NPS article

Question 3

Abrupt cessation of levodopa →

Answer 3

neuroleptic malignant syndrome, including severe muscle stiffness, autonomic instability and impaired consciousness.
(Ref: Deprescribing 2015, NPS article)

Question 4

Systemic corticosteroids for more than a few weeks→ ,

Answer 4

Sudden cessation may sometimes lead to an Addisonian crisis secondary to suppression of the hypothalamic-pituitary-adrenal axis
(Ref: Deprescribing 2015, NPS article)

Question 5

For psychotropic medicines,

–> approach to coming off the medication

Answer 5

the overall aim might be to reduce the dose by 25% each month, adjusting this according to the patient’s response.1

(Ref: Deprescribing 2015, NPS article)