Medication 35 Flashcards
Trade name/ brand name
Given by drug manufacturer. Property of that manufacturer
Pharmacology
Study of the effect of drugs on living organisms
Pharmacy
Art of preparing compounding and dispensing drugs
Pharmacopoeia
Book containing a list of products used in medicine, formulas and tests
Therapeutic effect
Desired effect
Side effect
Secondary effect, unintended
Adverse effects
Severe side effects
Palliative
Relieves symptoms only
Curative
Cures disease or condition
Supportive
Supports body function until other treatments or body can take over.
Substitutive
Replaces body fluids or substances
Chemotherapeutic
Destroys malignant cells
Restorative
Returns body to health
Drug tolerance
Person who has very low physiological response
Cumulative effect
Increasing response to repeated doses of a drug that occurs when the rate of administration exceeds rate of metabolism or excertion
Idiosyncratic effect
Unexpected and may be individual to a client. Under or over response
Drug interaction
Administration of one drug before, at the same time as, or after alters one or both.
Potentiating effect
Increased effect
Additive
Two of the same types of drug increase the action of each other
Synergistic effect
When two different drugs increase the action of one or another drug
Iatrogenic disease
Caused unintentionally by medical therapy
Generic name
Assigned by the United States adopted names and is used throughout drugs lifetime
Physiological dependence
Biochemical changes in body tissues, especially the nervous system
Alcohol
Psychological dependence
Emotional reliance on a drug to maintain a sense of well being, cravings
Cocaine
Drug habituation
Mild form of psychological dependence
Illicit drugs
Street drugs. Sold illegally
Half life
Time interval required for the body’s elimination processes to reduce the concentration of the drug by one half
Pharmacodynamics
Mechanism of drug action and the relationships between drug concentration and responses in the body
Receptor
Drugs specific target
Agonist
Produces response *** same as physiological or endogenous substance
Antagonist
Blocks or inhibits cell function by occupying receptor sites
Pharmacokinetics
Study of the absorption, distribution, bio transformation and excretion of drugs
Absorption
Process by which a drug passes into the blood stream
Distribution
Depends on circulation
Bio transformation
Detoxification or metabolism
Liver
Metabolites
Products of detoxified drugs
Active metabolite
Pharmacologic action
Inactive metabolite
No pharmacologic action
Excretion
Process by which metabolites and drugs are eliminated from the body
*urine and feces
Pharmacogenetics
Variation in drug response due to genetics
Ethnopharmacogy
Study of the effect of racial and ethnic responses to prescribed medication
Iron
Cause GI irritation
Can stain teeth
Parenternal
By needle
Food drug cosmetic act 1938
FDA requires labels be accurate and all drugs be tested for harmful effects
Durkham-Humphrey amendment 1952
Drugs must be sold with a prescription and not refilled without one
Kefauver-Harris amendment 1962
Requires proof of safety and effect for drug approval
Comprehensive drug abuse prevention and control act 1970
Categorizes controlled substances and limits how often a prescription can be filled
Standing order
Carried out indefinitely or may have termination date (BID for 7 days)
Medication reconciliation
The process of creating the most accurate list possible of all medications a patient is taking
Hypodermic syringe
Comes in 3 and 5 mL sizes
Tuberculin syringe
Calibrated in tenths and hundredths of a millimeter
Gauge of a needle
Larger the gauge, smaller the diameter of the needle
Tandem setup
Second container is attached to the line of the first container at the lower, secondary port
Percutaneous
Route of absorption through the skin
Ophthalmic medications
Eyes
Metered-dose inhaler
Handheld nebulizer
Lavage
Irrigation
Onset of action
Body initially responds to drug
Peak plasma level
Highest plasma level. Elimination equals absorption
Half life
Elimination process reduces concentration by one half
Plateau
Maintained drug concentration in plasma
Pharmacodynamics
Mechanism of drug action and relationships between drug concentration and responses in body
Agonist
Drug produces same type of response as the physiological or endogenous substance
Antagonist
Drug that inhibits cell function by occupying receptor sites
Pharmacokinetics
The study of absorption, distribution, bio transformation and excretion of drugs
Absorption
The process by which a drug passes into the bloodstream
Distribution
Depends on circulation
Bio transformation
Detoxification, metabolism
Metabolites
Products of bio transformation. Usually in liver
Intradermal
Tb syringe
#25-#27
1/4-5/8 inch
0.1 mL
Subcutaneous
1-2mL syringe or insulin #25 #30 for insulin 5/8 at 45 degrees 3/8 at 90 degrees 0.5-1mL
IM
Deltoid 1 mL syringe Ventrogluetal 3-5 mL syringe Deltoid #23-#25 gauge Ventrogluteal #21 or #22 gauge Deltoid: less than 1mL Ventrogluteal: 3 mL well developed
Tandem
Medicine administer intermittently or simultaneously with primary solution
Secondary port
Piggyback
Solely for intermittent drug administration
Primary port
Ophthalmic
Eyes
Otic
Ear
Metered dose inhaler
Handheld nebulizer
Lavage
Irrigation