Asepsis Flashcards
Resident flora
Collective vegetation in a given area
Disease
Detectable alteration in normal tissue function
Virulence
Microorganisms ability to produce disease
Communicable disease
Infectious agent can be transmitted to an individual by direct or indirect contact or as an airborne infection
Pathogenicity
Ability to produce disease
Opportunistic pathogen
Causes disease only in a susceptible individual
Asepsis
Freedom from disease causing microorganisms
Medical asepsis
Includes all practices intended to confine a specific microorganism to a specific area
CLEAN
Surgical asepsis
Sterile technique
Refers to those practices that keep an area or object free of all microorganisms
Sepsis
The condition in which acute organ dysfunction occurs secondary to infection
Bacteria
Most common infection causing microorganisms
Viruses
Consist primarily of nuclei acid and must enter living cells to reproduce
Fungi
Yeasts
Molds
Parasites
Live on other living organisms
Colonization
The process by which strains of microorganisms become resident flora
Local infection
Limited to specific part of the body where the microorganisms remain
Systemic infection
Microorganisms spread and damage different parts of the body
Bacteremia
When a culture of the persons blood reveals microorganisms
Septicemia
Bacteremia results in systemic infection
Nosocomial infections
Infections that originate in the hospital
Endogenous
Microorganisms that cause nosocomial infections that come from clients themselves
Exogenous
Microorganisms that cause nosocomial infections that come from the hospital
Nosocomial urinary tract
E. coli
Enterococcus
Pseudomonas
Cause of E. coli
Improper catheterization
Enterococcus species
Contamination of closed drainage system
Pseudomonas aeruginosa
Inadequate hand hygiene
Nosocomial surgical sites
Staphylococcus aureus (MRSA)
Enterococcus species
(VRE
Pseudomonas aeruginosa
MRSA cause
Inadequate hand hygiene
VRE cause
Improper dressing change technique
Latrogenic infections
Nosocomial, direct result of diagnostic or therapeutic procedures
Pathogenicity
Ability of the microorganisms to enter the body, susceptibility of the host, ability of microorganisms to live in hosts body
Reservoir
Sources of microorganisms
Carrier
Reservoir of a specific infectious agent that usually does not manifest any clinical signs of disease
Method of transmission
Direct
Indirect
Airborne
Direct transmission
Involves immediate and direct transfer of microorganisms from person to person
Indirect transmission
Either vehicle or vector
Vehicle borne
Any substance
Vector borne transmission
Animal or flying insect
Droplet nuclei
The residue of evaporated droplets emitted by an infected host. Can remain in air
Compromised host
Person at increased risk
Nonspecific defenses
Protect the person against all microorganisms, regardless of prior exposure
Specific (immune) defenses
Directed against identifiable infection agents
Nonspecific defenses include
An atomic and physiological Barriers and the inflammatory response
Inflammation
PAIN Swelling Redness Heat Impaired function
Physical agents
Mechanical objects. Trauma, heat, cold, radiation
Chemical agents
External irritants and internal irritants
First stage of inflammatory response
Vascular and cellular responses
Second stage of inflammatory response
Exudate production
Third stage of inflammatory response
Reparative phase
Vascular and cellular responses
Inflammation- blood vessels at site will constrict . Histamine will dialate and cause redness and heat.
Leukocytes
WBCs leak into interstitial spaces (swelling and pain appear
Pain in inflammation is caused by
Pressure of accumulating fluid on nerve endings and irritating chemical mediators
Leukocytosis
In response to leukocytes leaving blood, marrow produces more WBCs
Exudate
Fluid that escaped from the blood vessels, dead phagocytosis cells and dead tissue cells
Regeneration
Repair of injured tissues by regeneration or replacement with fibrous tissue
Granulation tissue
Early stages of regeneration
Antigen
Substance that induces a state of sensitivity or immune responsiveness (immunity)
Auto antigen
Proteins originate in a person’s own body, the antigen is called auto antigen
Humoral
Circulating immunity
B lymphocytes
Antibodies
Immunoglobulins
Defend against extra cellular phases of bacterial and viral infections
Active immunity
Host produces antibodies in response to natural antigens or artificial antigens
Passive immunity
Acquired
Host receives natural or artificial antibodies produced by another source
Cell-mediated defenses
Cellular immunity
Occur through T-cell system
Three main groups of Tcells
Helper
Cytotoxic T cells
Suppressor
Normal WBC count
4500-11000/ ml3
Cultures
Laboratory cultivation a of microorganisms a special growth medium
Nursing diagnosis risk of infection
Fever Imbalanced nutrition Acute pain Social isolation Anxiety
Major goals for clients susceptible to infection
Maintain or restore defenses
Avoid spread
Reduce or alleviate problems with infection
Supporting defenses of a susceptible host
Hygiene Nutrition Fluid Sleep Stress Immunizations
Antiseptics
Agents that inhibit the growth of some microorganisms
Disinfectants
Agents that destroy pathogens other than spores
Sterilization
Process that destroys all microorganisms, including spores and viruses
Four common methods of sterilization
Moist heat, has, boiling water, radiation
Infection
The growth of microorganisms in body tissue where they are not usually found