MDD

Question 1

Types of mood disorders x2

Answer 1

Depressive and Bipolar affective disorders

Question 2

Types of Bipolar disorders x5

Answer 2

Bipolar 1 and 2
Cyclothymic disorder
Bipolar disorder secondary to drugs or medical condition

Question 3

Types of depressive disorders x5

Answer 3

Major depressive disorder
Premenstrual dysphoric disorder
Disruptive mood dysregulation disorder
Depression secondary to substance abuse or medical condition

Question 4

Define major depressive disorder

Answer 4

An episodic mood disorder characterized by anhedonia and low mood for at least 2 seeks

Question 5

Which psychological factors can be a risk factor for MDD x3

Answer 5

Cormobidities
Trauma and stress
Neurodegenerative, chronic or psychiatric disorders

Question 6

Difference between MD episode and MDD x2

Answer 6

In MDD:
1. There is no other psychotic disorders that could cause the symptoms
2. There is no history of manic or hypomanic disorders

Question 7

Risk to self in MDD x5

Answer 7

Suicide
Self harm
Self neglect
Alcohol/ substance abuse
Not taking medication

Question 8

Risk to others in MDD x3

Answer 8

Violence
Neglect
Suicidal talks in front of children

Question 9

Risk from others in MDD x3

Answer 9

Abuse
Neglect
Exploitation

Question 10

Investigations for MDD x5

Answer 10

HIV
Toxicology
Cognitive tests
Urea & Creatinine
Thyroid function tests

Question 11

Endocrine disorders that mimic MDD x4

Answer 11

Hypothyroidism
Hyperparathyroidism
Addison’s disease
Cushing’s disease

Question 12

Differential diagnoses for MDD x4

Answer 12

1. Mood disorder secondary to medical condition
2. Mood disorder secondary to substance or medication
3. Manic episode with irritable mood or mixed episodes
4. Normal grief

Question 13

Which vitamin deficiencies can mimic MDD x2

Answer 13

B12
Folate

Question 14

When to consider antidepressants in MDD x3

Answer 14

1. In moderate/severe form of disease
2. Mild depression that persists after other interventions have failed
3. An initial presentation of mild depressive symptoms that have been there for 2 years

Question 15

MOA of antidepressants x3

Answer 15

Inhibition of monoamine oxidase
Inhibition of presynaptic reuptake of monoamines
Increase availability of monoamine precursors

Question 16

Biological management for MDD x3

Answer 16

SSRI- Selective serotonin reuptake inhibitors
SNRI - serotonin noradrenaline
MOAI - monoamine oxidase inhibitors

Question 17

Purpose of CBT in MDD

Answer 17

To help challenge the patients thoughts about themselves and the world

Question 18

Psychological management of MDD x4

Answer 18

Psychoeducation
Psychodynamic therapy
Cognitive behavioral therapy
Problem solving therapy

Question 19

Social management x3

Answer 19

Support groups
Family support
Financial assistance

Question 20

Which drugs cause symptoms of depression x5

Answer 20

Anticonvulsants
Beta blockers
Contraceptives - oral
Ca channel blockers
Corticosteroids

Question 21

DSM 5 criteria for MDD x5

Answer 21

1. 5/more symptoms of SIGE CAPS with2 being low mood and anhedonia for 2 weeks
2. Significant distress and impairment
3. Not attributable to substances/medical condition
4. Not due to any psychotic or schizophrenia spectrum disorder
5. Never been associated with a manic episode

Question 22

SIGE CAPS

Answer 22

Sleep disturbances
Interest loss
Guilt
Energy loss
Concentration
Appetite
Psychomotor
Suicide