MC Pathogen + Buzzwords - Infectious Disease Flashcards
viral conjunctivitis
adenovirus (swimming pool mc source)
bacterial conjunctivitis
staph or strep
neonatal conjunctivitis
day 1 - silver nitrate (chemical cause)
day 2-5 - gonococcal (need admit + IV)
day 5-7 - chlamydia MC
day 7-11 - HSV
otitis externa
pseudomonas
-alt: proteus, staph, s.epidermis, strep
acute otitis media & acute sinusitis
4 MC:
S. PNEUMO, H. influenza, moraxella catarrhalis, strep
chronic otitis media
2 MC: pseudomonas, staph
chronic sinusitis
bacterial: STAPH MC, pseudomonas
fungal: ASPERGILLUS MC, murcormycosis (immunocomp)
other: Wegener’s (bact) = necrotic
rhinitis (infectious)
rhinovirus
pharyngitis/tonsillitis
VIRAL MC overall - adeno, rhino, entero, EPV, RSV, flu
bacterial - GABHS/s.pyogenes mc
peritonsillar abscess
STREP, staph, polymicrobial
laryngitis
VIRAL MC - adeno, rhino, flu, RSV
bacterial - m.catarrhalis, mycoplasma pneumo
periorbital cellulitis
staph (so cover for mrsa)
suppurative parotitis or sialadenitis
staph
dental caries
strep mutans
acute osteomyelitis
STAPH AUREUS + strep (kids mc)
-salmonella pathognomonic for sickle cell
chronic (subacute) osteomyelitis
STAPH AUREUS
-s. epidermis in prosthetic joint infx
septic arthritis
STAPH AUREUS
- neisseria gonorrhoeae (sexual active adults - assoc w/ tenosynovitis)
- neonates - group B strep
- prosthesis - staph epidermis
gastritis
- -> h.pylori MC
- -> NSAIDs/ASA 2nd mc
- -> acute stress
- -> others (meds, alcohol, dz)
acute cholangitis
-mc gram neg enteric: E.COLI, klebsiella, enterobacter, b.fragilis
MC overall cause of gastroenteritis in adults in N. America
NOROVIRUS
- outbreaks - cruise ships, hospitals, restaurants
- vomiting predominant sx in most noninvasive diarrhea
MC cause of diarrhea in children (70%)
ROTAVIRUS
diarrhea: incubation period 1-6 hrs
MC food contamination (dairy, mayonnaise, meats, eggs)
STAPH AUREUS
BACILLUS CEREUS
- sx- V/HA/D, cramps
- tx- supportive, fluids
diarrhea: contaminated food and water; outbreaks during poor sanitation + overcrowding conditions (esp abroad)
- RICE WATER STOOLS
VIBRIO CHOLERAE (or vibrio parahemolyticus)
- gray, no fecal odor or pus
- may rapidly produce dehydration (up to 15L/day)
- tx- fluid replacement +/- TETRACYCLINES, FQ
diarrhea: assoc w/ raw shellfish, esp Gulf of Mexico
- RICE WATER STOOLS
VIBRIO PARAHEMOLYTICUS & V. VULNIFICUS
-tx- fluid replacement +/- TETRACYCLINES, FQ
MC cause TRAVELER’S DIARRHEA –> unsanitary drinking water/ice, unpeeled fruits
ENTEROTOXIGENIC E.COLI
diarrhea: org overgrowth 2ry to alteration of normal flora (mc after abx –> CLINDAMYCIN or chemo)
CLOSTRIDIUM DIFFICILE
MC cause of BACTERIAL ENTERITIS in US
MC ANTECEDENT EVENT IN POST-INFX GUILLAIN-BARRE SYNDROME
stool culture: gram neg, “S, COMMA, OR SEAGULL SHAPED” organisms
CAMPYLOBACTER ENTERITIS
diarrhea: fecal/oral
lower abd pain, EXPLOSIVE, WATERY DIARRHEA –> MUCOID, BLOODY
+/- FEBRILE SEIZURES IN CHILDREN
SHIGELLA (gram neg)
diarrhea: mucus + bloody OR PEA SOUP STOOLS
- mc source: poultry products, exotic pets (turtles)
SALMONELLA
diarrhea: ingestion of UNDERCOOKED GROUND BEEF, UNPASTEURIZED MILK/APPLE CIDER, DAY CENTERS, CONTAMINATED WATER
- PRODUCES CYTOTOXIN
ENTEROHEMORRHAGIC E.COLI 0157:H7
diarrhea: contaminated pork, milk, water + tofu
YERSINIA ENTEROCOLITICA
diarrhea: contaminated water from remote streams/wells
“beaver’s fever” or “backpacker’s diarrhea”
-frothy, greasy, foul
GIARDIA LAMBLIA
mc cause of chronic diarrhea in patients w/ AIDS
cryptosporidium
-fecal-oral transmission
malabsorption - mc farmers around soil
tropheryma whippelii
TRANSMISSION: PIGEON/BIRD DROPPINGS
CRYPTOCOCCOSIS
ASSOC W/ SOIL CONTAINING BIRD/BAT DROPPINGS IN MISSISSIPPI & OHIO RIVER VALLEYS
histoplasmosis
CXR: “FUNGAL BALL”
ASPERGILLOMA
BX: DUSKY, NECRTOIC TISSUE (NOSE)
ASPERGILLUS
SINUSITIS that spreads to the orbits, palate + brain
-BLACK ESCHARS of nasal mucosa, palate + cyanosis
mucormycosis
BX: SEPTATE HYPHAE W/ REGULAR BRANCHING AT WIDE ANGLES
ASPERGILLUS
BX: NON-SEPTATE BROAD HYPHAE W/ IRREGULAR RIGHT-ANGLE BRANCHING
MUCORMYCOSIS
grows in SOIL IN ARID/DESERT REGIONS OF SOUTHWESTERN US, MEXICO, SOUTH + CENTRAL AMERICA
coccidioidomycosis “valley fever”
occurs MC IMMUNOCOMPETENT MEN
-OUTDOOR ACTIVITIES (AROUND SOIL OR DECAYING WOOD) IN CLOSE PROXIMITY TO WATERWAYS (great lakes, Ohio, Mississippi river valley)
blastomycosis
PAINFUL GENITAL ULCERS –> BOBO FORMATION
chancroid (haemophilus ducreyi)
+ KERNIG’S SIGN + BRUDZINSKI’S SIGN
neisseria meningitidis (meningococcal meningitis)
mc cause epiglottitis
haemophilus influenzae
rabbits as reservoir, bites, or ingestion of infx meat
tularemia (francisella tularensis)
diseases w/ eschars
TULAREMIA ANTHRAX LEISHMANIASIS COCCIDIOIDOMYCOSIS MUCORMYCOSIS
- GOAT, SHEEP, CATTLE HOGS MC ANIMAL VECTOR
- INGESTION OF INFECTED UPASTEURIZED MILK + CHEESE
brucellosis
SAFETY PIN APPEARANCE OF ORGANISMS
PLAGUE (YERSINIA PESTIS)
FOURNIER’S GANGRENE
nec fascititis of PENIS/SCROTUM
-MC GABHS
OCCUPATIONAL DZ FOLLOWS SKIN ABRASION, PUNCTURE WOUND FROM RAW FISH, SHELLFISH, RAW MEAT/POULTRY
ERYSIPELOID
MC FOUND IN CONTAMINATED FOOD: COLD DELI MEATS, UNPASTEURIZED DAIRY
LISTERIA
- ADULT: CANNED/SMOKED/VACUUM-PACKED FOODS
- INFANT: INGESTION OF HONEY OR DUST SPORES
BOTULISM
DILATED, FIXED PUPILS, DRY MOUNT, DYSPHAGIA, DYSARTHRIA, DYSPHONIA
- DESCENDING, DECREASED MUSCLE STRENGTH –> flaccid paralysis
- “FLOPPY BABY SYNDROME” newborn
BOTULISM
CHANCRE - PAINLESS ULCER AT INOCULATION SITE
SYPHILIS
CHONDYLOMA LATA
SYPHILIS
-wart-like, moist lesions involving mucous memb, esp near chancre site - contagious!
HUTCHINSON TEETH (notches), SADDLE-NOSE DEFORMITY
CONGENITAL SYPHILIS
ARGYLL-ROBERTSON PUPIL
+/- TERTIARY SYPHILIS
small, irregular pupil that constricts normal to near accommodation but doesn’t constrict/react to light
BLANCHING, ERYTHEMATOUS MACULAR RASH FIRST ON WRISTS/ANKLES –> PALMS/SOLES, SPREADS CENTRAL OVER 2-3 DAYS
ROCKY MT SPOTTED FEVER (rickettsia ricketsii)
CORNEAL STROMAL RING INFILTRATE
ACANTHAMOEBA KERATITIS
FEMALE ANOPHELES MOSQUITO
PLASMODIUM
PARASITES IN RBC
MALARIA
ixodes TICK
transmits:
BABESIOSIS
EHRLICHIOSIS
LYMES
Smear: parasites w/in RBC, esp PATHOGNOMONIC TETRADS (MALTESE CROSS)
BABESIOSIS (babesia microti)
-tick bite, northeast US
enterobiasis
pinworm
Head CT/MRI +/- show RING-ENHANCING LESIONS
TOXOPLASMOSIS
CNS LYMPHOMA
- ROMANA’S SIGN: UNILAT PERIORBITAL SWELLING
- CHAGOMA: INFLAM NODULE @ BITE SITE
- CHF
CHAGAS DISEASE (trypanosoma cruzi, protozoa)
vector: assassin bug
latin america and up to texas
chagas disease (trypanosoma cruzi, protozoa)
PERIORBITAL EDEMA, MYOSITIS, EOSINOPHILA
TRICHINOSIS
parasitic roundworm from undercooked meat, pork
MORULAE IN WBC
-MULBERRY-SHAPED AGGREGATES IN CELLS
EHRLICHIOSIS
RAMSAY-HUNT SYNDROME
VZV - Facial Nerve (CN 7) - otalgia, lesions on ear/TM, facial palsy, ear sx
HUTCHINSON’S SIGN
(different from Hutch Teeth)
VZV - lesion on nose usually heralding ocular involvement (CN 5, trigeminal)
rash in different stages simultaneously; doesn’t usually involve palms/soles
varicella / chicken pox
lesions appear in same stage simultaneously, involves palms/soles
variola / small pox
prodrome: Cough, Coryza, Conjunctivitis
-maculopapular brick-red rash beginning at
hair line/face –> extremities; lasts 7 days
-koplik spots on buccal mucosa
rubeola / measles
maculopapular pink-light red spotted rash on face –> extremities; lasts 3 days
-photosensitivity and arthralgias
rubella / german measles
3 days high fever (child appears well) –> fever resolves and pink/maculopapular rash (STARTS ON TRUNK, GOES TO FACE)
roseola / sixth’s disease
“slapped cheek appearacne” w/ circumoral pallor –> lacy rash on body
erythema infectiosum / 5ths disease
- arthropathy in older adults
- aplastic crisis in sickle cell
- inc fetal loss in pregnancy
vesicular lesions on red base w/ erythematous halo in oral cavity –> vesicles on hands/feet (includes palms/soles)
coxsackie a virus / hand, foot mouth
flu-like –> maculopapular rash trunk + axilla –> extremities but spares face, palms, soles
-flushed face, hearing loss, conjunctivitis
endemic typhus
local s. aureus infx –> fluid-filled blisters w/ positive NIKOLSKY SIGN (sloughing w/ gentle pressure)
-painful, diffuse red rash, starts centrally
scalded skin syndrome
- prodrome: fever, conjunctivitis, cervical lymphadenopathy
- STRAWBERRY TONGUE, EDEMA/DESQUAMATION OF PALMS/SOLES
kawasaki
-rare complication is myocardial infarction and coronary artery involvement
- STRAWBERRY TONGUE, SANDPAPER RASH, facial flush w/ circumoral pallor
- FORCHHEIMER SPOTS: small red spots on soft palate
scarlet fever
chancroid
- caused by HAEMOPHYLIS DUCREYI
- tx AZITHRO
maculopapular rash after amox/amp*
INFECTIOUS MONO
rash from wrist/ankles –> trunk*
outdoor hx
rocky mtn spotted fever (rickettsia)
-tx w/ doxy, even kids
jarisch-herxceimer rx*
systemic inflam response caused by dying spirochetes when syphilis treated
acute HIV infx sx**
fever, fatigue, rash, HA, lymphadenopathy, pharyngitis, myalgia, arthralgia, N/V/D, night sweats