Manual, Semiautomated, and Point-of-Care Testing in Hematology

Question 1

1. A 1:20 dilution of blood is made with 3% glacial acetic acid
   as the diluent. The four large corner squares on both sides
   of the hemacytometer are counted, for a total of 100 cells.
   What is the total WBC count (3109/L)?
   a. 0.25
   b. 2.5
   c. 5
   d. 10

Answer 1

b. 2.5

100 X 20 X 10^6/ 0.8

Question 2

2. The total WBC count is 20 3 109/L. Twenty-five NRBCs per
   100 WBCs are observed on the peripheral blood film. What
   is the corrected WBC count (3109/L)?
   a. 0.8
   b. 8
   c. 16
   d. 19

Answer 2

c. 16

Question 3

3. If potassium cyanide and potassium ferricyanide are used
   in the manual method for hemoglobin determination, the
   final product is:
   a. Methemoglobin
   b. Azide methemoglobin
   c. Cyanmethemoglobin
   d. Myoglobin

Answer 3

c. Cyanmethemoglobin

Question 4

4. Which of the following would not interfere with the result
   when hemoglobin determination is performed by the cyanmethemoglobin method?
   a. Increased lipids
   b. Elevated WBC count
   c. Lyse-resistant RBCs
   d. Fetal hemoglobin

Answer 4

d. Fetal hemoglobin

Question 5

5. A patient has a hemoglobin level of 8.0 g/dL. According to the
   rule of three, what is the expected range for the hematocrit?
   a. 21% to 24%
   b. 23.7% to 24.3%
   c. 24% to 27%
   d. 21% to 27%

Answer 5

d. 21% to 27%

Question 6

6..Calculate the MCV and MCHC for the following values:
RBCs 5.00x 1012/L
HGB 9 g/dL
HCT 30%

Answer 6

B.

Question 7

7. What does the reticulocyte count assess?
   a. Inflammation
   b. Response to infection
   c. Erythropoietic activity of the bone marrow
   d. Ability of red blood cells to form rouleaux

Answer 7

c. Erythropoietic activity of the bone marrow

Question 8

8. For a patient with the following test results, which measure
   of bone marrow red blood cell production provides the
   most accurate information?
   Observed reticulocyte count 5.3%
   HCT 35%
   Morphology—moderate polychromasia
   a. Observed reticulocyte count
   b. Corrected reticulocyte count
   c. RPI
   d. ARC

Answer 8

c. RPI

Question 9

9. Given the following values, calculate the RPI:
   Observed reticulocyte count 6%
   HCT 30%
   a. 2
   b. 3
   c. 4
   d. 5

Answer 9

a. 2

Question 10

10. Which of the following would be associated with an
    elevated ESR value?
    a. Microcytosis
    b. Polycythemia
    c. Decreased globulins
    d. Inflammation

Answer 10

d. Inflammation