Lymphoma Flashcards

1
Q

hodgkins arise from what cells

A

B-CELLS

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2
Q

hodgkins clinical pres

A
  • REED STERNBERG
  • giant conn tissue cell containing 1 or 2 large nuclei
  • presence determines hodgkins or non-hodg
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3
Q

hodgkins staging system

A

ANN ARBOR

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4
Q

waldeyer’s ring (nose/mouth area) is composed of

A
  • cervical
  • preauricular
  • occipital lymph nodes
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5
Q

spleen is the largest?

A

lymph node

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6
Q

hodgkins total nodal irradiation aka

A

extended field irradiation

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7
Q

hodgkins mantle fld blocks what?

A
  • lungs
  • humeral heads
  • larynx
  • cord
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8
Q

hodgkins subdiaphragmatic fld includes

A
  • para-aortics

- spleen

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9
Q

hodgkins peds periaortic sup field border

A

T10

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10
Q

non-hod xrt sensitivity

A

sensitive to rad

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11
Q

hodgkins xrt dose for cure

A

40-50 Gy

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12
Q

hodgkins most common site

A

NECK & SLCV

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13
Q

hodgkins 1/3 present with ?

A

“B” symptoms

-enlarged spleen, abd, bony tenderness, pleural effusion

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14
Q

“B” symptoms are ?

A
  • enlarged spleen
  • abdominal & bony tenderness
  • pleural effusion
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15
Q

hodgkins xrt fields treated

A
  • ap/pa mantle fld
  • ap/pa para-aortic
  • tx of pelvis, retroperitoneal, inguinals
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16
Q

hodgkins xrt dose

A
  • 35-40Gy w/o chemo

- 20-25 Gy w/chemo

17
Q

hodgkins mantle ant field superior border

A

inf mandible

18
Q

hodgkins mantle ant field inferior border

A

insertion diaphragm

19
Q

hodgkins mantle ant field lateral border

A

axillary nodes

20
Q

hodgkins mantle post field superior border

A

occipital nodes

21
Q

hodgkins mantle post field inferior border

A

diaphragm (T9-10)

22
Q

hodgkins mantle post field lateral border

A

axillary nodes

23
Q

hodgkins mantle field CAX located

A

suprasternal notch

24
Q

hodgkins subdiaphragmatic field inf border

A

L4-5 or bifurcation of aorta

25
Q

hodgkins subdiaphragmatic field blocks what

A
  • liver
  • kidneys
  • pelvic bone
  • reproductive organs
26
Q

hodgkins peds xrt dose

A
  • low doses: 36-44 Gy gross disease or 30-36 Gy microscopic
  • small vol
  • RAD= TX OF CHOICE
27
Q

hodgkins peds periaortic field inf border

A

L4/5

28
Q

hodgkins peds periaortic field lat border

A

9-10 cm wide

29
Q

hodgkins peds pelvis field sup border

A

L5

30
Q

hodgkins peds pelvis field inf border

A

2cm below ischial tuberosities

31
Q

hodgkins peds pelvis field lat border

A

2cm beyond pelvic inlet

32
Q

non-hod xrt prognosis

A

only small portion obtain cure b/c of high prob of spread

33
Q

non-hod xrt stage I/II low grade dose

A

35-45 Gy

34
Q

non-hod xrt intermed stage regimen

A

chop followed by 30-35 Gy

35
Q

non-hod xrt follicular & mantle dose

A

30-36 Gy boost 36-40 Gy

36
Q

non-hod xrt TBI dose

A

palliation in advanced nodular lymphcytic lymphoma= 1.5 Gy for 5 wks