General Brachytherapy Flashcards
radium-226 decay process of ? isotope results in stable ? isotope?
part of decay process of Uranium-238 resulting in stable Pb-206
Ra/daughter equilibrium takes how long to reach?
30 days
uniform sources have same concentration of radioactivity through entire ?
length
Cs-137 decays ?% in 6 months
1%
Cs-137 used for what implants?
gyn
Pd-103 decays by ? to ?
by e- capture to Rh-103
P-32 t1/2
14.3 days
P-32 used for what implants
intravascular & peritoneum
Ir-192 decays ? % per day
1%
Au-198 decays by what to what
B- to Hg-198
I-125 emits what
pure gamma emitter
Sr-90 emits what
pure beta emitter
activity aka
- strength of source
- rate of decay
- # of nuclei decaying per sec
decay constant incr then activity ?
incr; directly prop
decay constant is the total # ? that decay per unit time
total # of atoms that decay per unit of time
t1/2 incr then overall activity ?
decr; inv prop; decay decr
average E is the avg value of ? from each isotope
all emitted photons from each isotope
specific activity is the activity per unit ? of radioactive material
mass
specific activity decr then activity per gram ?
decr; directly prop
Ci is ? dps
3.7 x 10^10 dis/sec
Bq is ? dps
1 dis/sec
fletcher suite applicator is made up of ?
- uterine tandem
- cervical colpostats (ovoids)
- capsules for uterine
heymans capsules are used when ? still intact
uterus
delclos is used for ? afterloading
uterine-vag
burnett applicator is use for tx of ?
tx vaginal tissues
Ra-226 dose distrib based on
calcs
square or rectangular implants aka
planar implant
multiple plane implants are spaced how far apart
1 cm apart & parallel
with volume implants, more than ? planes of sources are used
2
quimby/memorial system is similar to ?
paterson
quimby system uses what calc system
long & away
paris system is ? distribution like ?
UNIFORM distrib like quimby
trocars are what used for what implants
hollow needles used for interstitial implants
anisotropy results when source construction causes ? dose distribution
non-uniform
mean life is the ? lifetime for decay of isotope
avg lifetime
exposure rate constant aka
gamma factor
objectives for implant dosimetry is to determine distribution of sources & type to provide ? dose distribution
optimum
autoradiograph determines
uniformity
full strength needles have ? mg Ra/cm
0.66 mg Ra/cm or 0.5
1/2 strength needles have ? mg Ra/cm
0.33 mg Ra/cm or 0.25
activity of 1g of Ra-226 in Ci
0.988 Ci
brachy shielding public continuous freq
0.1 rem or 1 mSv
brachy shielding public infreq
0.5 rem or 5 mSv
brachy shielding occupational
5 rem or 50 mSv
brachy dose in any UNRESTRICTED are must not exceed
2 mrem in 1 hr
threshold dose for hospitalized pts ? mCi
30 mCi
dose before release of implant pts ? mSv per hr @ ? distance
< 0.5 mSv per hr @ 1 m
waiting room adjacent to pt brachy room dose rate
below 2 mR/hr (2 mrem/hr) no action req’d
ophthalmic plaque isotopes used
- Co-60
- I-125
- Ru-106
- Ir-192
brain brachy isotope needs high/low activity?
high activity
annual report given to workers who exceed ? % of occup limit
10%
max leakage for walls, floors, etc ? mrem/wk
< 100
occupational workers per week
100 mrem
controlled area ? per hr or ? per wk
2 mrem/hr or 0.1 rem/wk
radiation area ? mrem/hr
5
brachy calib dosimetric protocol
TG-43
gyn low dose implants point A ? cGy/hr
50-60 cGy/hr
gyn low dose implants point B ? cGy/hr
18-20 cGy/hr
LDR dose rate definition ? cGy/hr
40-200 cGy/hr
MDR dose rate definition ? cGy/hr
200-1200 cGy/hr
HDR dose rate definition ?cGy/hr
> 1200 cGy/hr
Ra-226 to Cs-137 conversion
10mgRa= 25mCi
cumulative implant dose formula
1.44 x t1/2 x Do
shielding for stored radionuclides & generators reduce rad levels to < ? mrem/hr @ what distance
2 mrem/hr @ 1 m
Cs-137 decays to what? by what kind of decay?
decays by B- to Ba-137
Co-60 decays ? % per month
1%
Co-60 decays to what by what kind of decay?
decays by B- to Ni-60
Pd-103 is a ? emitter
pure gamma emitter
Ir-192 is created by ?
neutron activation in reactor
specific activity unit
Ci/g
1 Bq = ? Ci
2.7 x 10^-11 Ci
fletcher suite applicator produces a ? isodose distribution
pear shaped
ovoids are stabilized with
packing which also pushes bladder & rectum away
point A dose rate
50-60 cGy per hr
point B dose rate
18-20 cGy per hr
delclos allows for simultaneous tx of
- uterus
- vag walls
- cervix
packing for Burnett applicator is
at least 1.5cm
vag cylinder can be used for what other type of tx
interstitial
paterson parker provides dose of ? % within implanted area
+10% w/i implanted area (higher dose in periphery area)
paterson parker uses ? distribution to produce ? distribution
NON-UNIFORM; UNIFORM
multiple plane implants area should be reduced ? % for each uncrossed end
10%
volume implants are used for ? implants where activity is evenly spread out inside an organ or structure
seed reduced 7.5% uncrossed ends
in volume implants, dose is reduced by ? % at uncrossed ends
7.5
quimby memorial system uses ? distribution of activity to give ? dose
UNIFORM distribution; NON-UNIFORM dose
quimby prescribes ? arrangement of sources
uniform
quimby results in ? dose distribution with high/low dose in ? region
NON-UNIFORM dose distrib w/HIGH dose in CENTRAL region
quimby system used to plan what tx site
breast implants
paris system is used for implants with removable long lines of ? isotope
Ir-192
paris system reference dose is ? % of basal dose
85%
paris system has ? % decrease on uncrossed ends
15%
exposure rate constant is the exposure at ? distance from source
1 meter from radioactive source of known activity
exposure rate constant is the exposure at ? distance from ? volume of Ra filtered by ? mm of platinum
1cm, 1mg or 1mCi, 0.5 mm
leakage of sources has to be below
0.005 uCi
isotope used frequently for brain
I-125 (40 mCi/seed)
I-131 comes in what form
liquid or capsule
how does body eliminate I-131
excreted in urine
I-131 emits?
emits gamma & beta
Sr-90/Y-90 isotopes are loose/sealed
sealed
Sr-90/Y-90 emits
emits only low E beta particles