Intravascular Brachy Flashcards
restenosis can be reduced by ? irradiation with ?
intraluminal irrad w/balloon angioplasty
arteries can be blocked by
atherosclerosis or plaque
target volume of artery is ? cm in length
2-5 cm
tx planning for intravascular requires a ? conformal dose distribution
high
depth dose for intravascular is ? from center
2 mm
most common sources for temp intravascular
catheter based sealed sources
most common sources for perm intravascular
radioactive stents
intravascular temp dose ? Gy
15-20 Gy
pros beta over gamma for activity in intravascular
high specific activity
cons of beta for intravascular re: falloff
extremely rapid radical falloff
beta/gamma better in terms of dose rate per unit-activity for intravascular?
beta better
beta/gamma better in terms of radical dose distrib for intravascular
gamma better
Ir-192 used in intravasc
yes
Cordis Checkmate used for what brachy
intravascular
cordis checkmate with intravasc uses what source
Ir-192
guidant galileo with intravasc uses what source
B sources (P-32)
nova beta-cath intravasc uses what source
B of Sr/Y-90
ß liquid filled balloon advantage in tx planning
centering & dose conformity
radioactive stents use what sources
P-32, Y-90, V-48
bypass surgery can be tx using
intravascular brachy
PTCA (percutaneoustransluminal coronary angioplasty) can be tx using
intravascular brachy
high restenosis (problem- from clotting or neointimal growth) can be tx using
intravascular brachy
target volume of artery is ? thickness
0.5-2 mm
tx planning for intravascular gives a ? dose beta & ? dose rate & greater protection than ?
high; higher; gamma
intravascular temp source location= ? from center
2 mm
intravascular dose rate= ?Gy/min
5 Gy/min or greater
pros beta vs gamma for t1/2 for intravascular
longer t1/2
I-125 used for intravasc?
yes
Pd-103 used for intravasc?
yes
P-32 used for intravasc?
yes
Sr/Y-90 used for intravasc?
yes
ß filled balloon isotopes used
P-32, Y-90, Re*-188 (preferable)
radioactive stents disadvantage of dose
dose inhomogeneity b/c of structure of stent