Bone, Cartilage, Soft Tissue Sarcoma Flashcards
bone ca staging system
enneking staging system
bone ca mets location
almost all sarcomas met to lung, esp peripheral
osteosarcoma detection on radiographs
SUNBURST pattern caused by outward growth of bony spicules
chondrosarcoma most common location
prox femur
chondrosarcoma spread
lung
fibrosarcoma location
long tubular bones= femur, tibia
fibrosarcoma spread
lung
giant cell ca epidemiology
commonly seen in previously rad tx fld
giant cell ca location
- MOST COMMON AROUND KNEE
- long bones= femur, tibia
- also prox humerus, prox femur, sacrum, pelvis
ewing’s location
- DIAPHYSIS
- any bone, any part of body & soft tissue
- most common lower half
- most common in diaphysis, less metaphysis, rare epiphysis
Ewing’s detection on radiographs
ONION SKIN APPEARANCE
ewing’s xrt field margins
- lat strip norm tissue spread
- usu 4-5 cm margin
mm etiology
increase plasma cells
mm location
- any bone
- vert bodies rare
mm tx XRT
30 Gy for pain control
mets location
- vert bodies
- pelvis
- ribs
sts spread
- PRIMARY SPREAD= HEMATOLOGIC
- local growth patter longitudinal axis of primary site compartment
- lung
- lymph nodes- rare
sts shrinking fld technique
- entire compartment 10 cm margin, then 5 cm margin, then 2-3 cm margin
- leave 1-3 cm strip skin & soft tissue to avoid fibrosis & lymphedema
sts p+ or brachy isotopes
Ir-192 or I-125
sts intraoperative e- rad dose
10-20 Gy
sts pre-op dose
50 Gy
sts post op dose
65-75 Gy
osteosarcoma XRT
- RADIORESISTANT
- xrt used for pain but cure unusual
chondrosarcoma XRT
RADIORESISTANT
fibrosarcoma XRT
palliation
giant cell ca XRT
RADIOSENSITIVE= control or palliation
ewing’s tx XRT
55-60 Gy
Sr-89 emits
beta emitter
Sr-89 seeks
osteoblastic areas
Sr-89 t1/2
50.5 days
Sr-89 therapeutic effect
15 months; 1-3 wks for relief
Sr-89 readministered how often
every 90 days
sts epidemiology children
RHABDOMYOSARCOMA most common
