Lymphatics 112 Final Wilson Flashcards
Lymph
Fluid that is picked up by lymphatic vessels`
Lymph Nodes
Principal lymphoid organs of the body
Lymphatic trunk,
Drain fairly large areas of the body; formed by the largest collecting vessels uniting
Lymphatic duct,
Area that receives lymphatic drainage
lymphatics,
Elaborate networks of drainage vessels that collect eh excess protein-containing interstitial fluid and return it to the bloodstream
afferent /efferent lymphatic vessels,
- Afferent lymphatic vessels is where the lymph enters the node
- Efferent lymphatic vessels is where the lymph exits the node
MALT (mucosae associated lymphoid tissue)
Protects the digestive and respiratory systems from foreign matter
Hilum
The indented region on the concave side of node
Cortex
(outer) contains densely packed lymphocytes and scattered macrophages
Medulla
(inner) contains fewer lymphocytes and thymic (Hassall’s) corpusles
capsule trabeculae,
extends to divide the node into a number of compartments
Stroma
The network that supports the other cell types in lymphoid organs and tissues
Lacteals
Set of lymphatic capillaries that transport absorbed fat from the small intestine to the bloodstream
Peyer’s patch
(aggregated lymphoid nodules) large clusters of lymphoid follicles, structurally similar to the tonsils
metastatic cancer sites
lymph nodes
ruptured spleen,
blood spills into the peritoneal cavity. Can often repair itself.
role of lymph system
- Fluid balance (lymphatic vessels/system)
- Immunity/defense (lymphoid organs)
- Nutrition/digestion (lacteals; found in gastro tract)
organs in system,
- Spleen (largest lymph organ)
- Thymus
- Tonsils (simplest lymphoid organ)
- Peyer’s patches (in intestine)
- Appendix
permeability of lymph capillaries,
- Endothelial cells forming the walls of lymphatic capillaries are not tightly joined
- Collagen filaments anchor the endothelial cells to surrounding structures so that any increase in interstitial fluid volume opens the mini valves
flow of lymph (from capillaries to what to what, etc.),
capillaries vessels trunks ducts
where does lymph drain?
Into the large neck veins of the cardiovascular system
• thoracic duct into left subclavian trunk
• right lymphatic duct drains into right subclavian trunk
How is it drained from each side of the body?,
- Thoracic duct: receives lymph from all of body EXCEPT right upper limb and right side of head and thorax.
- Right lymphatic duct: drains lymph from the right upper limb and right side of head and thorax
5 cell types found in lymph tissue/roles of each
- Lymphocytes (mature into T cells or B cells): Protect against antigens
- Plasma cells: secrete antibodies
- Macrophages: Phagocytosis; active T cells
- Dendritic cells: spiny; capture antigens and deliver to nodes
- Reticular cells: fibroblast-like; produces stroma reticular fiber network in lymph organs.
role/anatomy spleen
site for lymphocyte proliferation and immune surveillance and response
• 5 inch organ between stomach & diaphragm
• Stroma consists of capsule, trabeculae, fibers, and fibroblasts
• Parenchyma consists of white pulp and red pulp
o White pulp: where immune function takes place
o Red pulp: where worn-out RBC’s and blood borne pathogens are destroyed
role/anatomy thymus (how does thymus different from other lymph organs?),
Where T lymphocytes become able to defend us against specific pathogens in the immune response
• Description: 2 lobed organ located in mediastinum
• Structure: Capsule & trabeculae divide it into lobules with medulla and cortex
• Hassall’s corpusles
- Increases in size and is most active during childhood
- stops growing during adolescence and then gradually atrophies
role/anatomy tonsils
- Simplest lymphoid organs
* Crypts trap and destroy bacteria and particulate matter
