Lymphatic Tissue and Organs Flashcards

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1
Q

Primary lympathic tissue

A

site of development of maturation of lymphocytes into immuncompetent cells

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2
Q

Two kinds of primary lymphatic tissues

A

bone marrow

thymus

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3
Q

3 kinds of secondary lymphatic tissue

A

lymph nodes
MALT
Spleen

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4
Q

Function of secondary lymphatic tissues

A

confrontation with antigens of pathogens occurs here

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5
Q

Lymph Nodes

A

filter lymph

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6
Q

MALT

A

surveillance

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7
Q

Spleen

A

filters blood
largest lymphatic organ
site of B and T lymphocyte proliferation
perpetual graveyard for cells

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8
Q

GALT

A

gut associated lymphatic tissue

in lamina propria of GI tract

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9
Q

BALT

A

bronchus associated lymphathic tissue

located in lamina propria of respiratory tract

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10
Q

GU tract

A

found in lamina propria of gentiourinary tract

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11
Q

Lamina Propria

A

latin for first layer

loose CT just inside epithelium

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12
Q

What cell types are seen in diffuse lymphatic tissue

A

lymphocytes
monocytes
macrophages
plasma cells

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13
Q

Solitary Lymphatic Nodules

A

are temporary

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14
Q

Aggregates of Lymphatic Nodules

A

are permanent. ex) peyer’s patches, appendix, BALT

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15
Q

Tonsils

A

aggregates of Lymphatic Nodules with B-lymphocytes

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16
Q

How can you tell it’s a palatine tonsil

A
  • stratified, squamous, nonkeratinized epithelium
  • secondary lymphatic nodules
  • crypts
  • cap made of dense irregular collagenous CT
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17
Q

Regions of lymph nodes

A

cortex and medulla

18
Q

Convex surface of lymph vessel

A

where lymph vessels bring lymph to the lymph node

19
Q

Concave surface of lymph vessel

A

bottom surface

has hilum

20
Q

Sinuses

A

pathogens and toxins are filtered out here

21
Q

Lymph node parechyma

A

cellular part

22
Q

Where are B lymphocytes found

A

nodules/cortex

23
Q

Where are T lymphocytes found

A

paracortex

24
Q

2 sources of lymphocytes

A

high endothelial venules in paracortex (main source)

afferent lymph vessels

25
Q

Where do T lymphocytes mature

A

thymus.

but originate in bone marrow

26
Q

Where are the most immature cells found

A

outer layer of cortex

27
Q

Where are the most mature cells found

A

inner layer of cortex

28
Q

Medulla

A

innermost layer where mature, immocompetent lymphocytes reach after tehy travel through the cortex

29
Q

What does the thymus NOT have?

A
  • afferent lymphatic vessels
  • 3D reticular fiber framework
  • lymphatic nodules
  • B-lymphocytes
  • sinuses or sinusoids
30
Q

Type I Epithelioreticular cells

A

create an antigen proof compartment for the T-lymphocytes in the cortex

31
Q

Blood Thymus barrier

A

isolates T-lymphocytes of the cortex from macromolecules circulating in the blood

32
Q

What is the blood thymus barrier made of?

A

cortical capillary endothelium
basal lamina
macrophages
type I epithelioreticular cells

33
Q

Type VI epithelioreticular cells

A

form hassall’s corpuscles in the medulla

34
Q

Type II epithelioreticular cells

A

form a 3D reticulum with their cell processes to suspend T-lymphocytes in the cortex

35
Q

Type III epithelioreticular cells

A

isolate cortex from medula

36
Q

Type IV epithelioreticular cells

A

similar to type III

found at corticomedullary junction, isolating cortex from medulla

37
Q

Type V epithelioreticular cells

A

similar to type II

form a 3D reticulum with their cell processes to suspend T-lymphocytes in the medulla

38
Q

DiGeorge’s Syndrome

A

developmental disorder
cannot produce T lymphocytes
death from infection

39
Q

What is parenchyma of spleen divided into

A

red pulp (majority is this) and white pulp (smaller islands formed by lymphatic islands)

40
Q

Red Pulp Cord (Cord of Billroth)

A

contains macrophages

41
Q

Open circulation of spleen

A

arterial capillaries end near the sinusoids, and blood from these capillaries seeps into splenic cords and then into splenic sinus