Lymphatic System (Exam 2) Flashcards
What are the 3 functions of the Lymphatic System?
- Drain excess interstitial fluid
- Transport dietary lipids
- Immune response (T cells and B cells mostly)
What are the 4 major components of the Lymphatic System?
- Lymph
- Lymphatic vessels
- Lymphatic tissue
- red marrow
In comparison to blood capillaries, lymphatic capillaries differ in what two ways?
- they have a slightly larger diameter
- they permit interstitial fluid to flow in, but not out
Describe the flow of lymph from the capillaries
Capillaries > vessels > ducts > Junction of internal jugulars and subclavian veins
Lymphatic vessels are more similar to ___ than ___.
more similar to veins than arteries
What is lymph?
Excess filtered fluid from blood capillaries that drains into lymph vessels.
Lymph contains most components of blood plasma except ____. Why?
except proteins.
- this is because it originated in blood
What is the function of the primary lymphatic organs?
to provide a place where lymphocytes (B and T cells) can form and become immunocompetent/mature
- both B and T cells are “born” in the bone marrow
- T cells have to migrate to the thymus to eventually achieve immunocompetence
What are the 2 primary lymphatic organs?
the red bone marrow and the thymus gland
What is the function of secondary lymphatic organs?
they activate lymphocytes
What are the 3 secondary lymphatic organs?
- lymph nodes
- spleen
- connective tissue capsule
What is the secondary lymphatic tissue?
lymphatic nodules (no connective tissue capsule)
Describe the shape of the thymus, its function, and size in adolescents vs adults
Shape: Bi-lobed
Function: Site where T-cells mature (in cortex/inner medulla)
Size in adolescents vs adults: Larger in adolescents than in adults; thymus atrophies with age due to immune system being more fully developed
What is the function of lymph nodes?
they function as a filter for lymph
Describe the lymph node.
- covered with a capsule
- trabeculae (roadways) divide node
- Outer cortex has nodules (B cell clusters)
- Inner cortex has T cells
- Medulla has B cells
- Macrophages
- Eliminate threat before material emerges from lymph node
- Reticular fibers trap foreign substances
- Most important fiber in cell
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The spleen in like…
…a lymph node for blood
What are the two types of pulp in the spleen?
- White pulp
- Red pulp
Name the 3 cell types in white pulp and what their overall function is
- B cells
- T cells
- Macrophages
They clean blood entering through the splenic artery
What are the 3 functions of the red pulp?
- Removal of deficient blood cells and platelets
- Storage of platelets
- Fetal hemopoiesis
Is the spleen essential?
No, not in adults
What are lymphatic nodules?
Mucosa-associated lymphatic tissue (MALT)
What is a Mucosa-associated lymphatic tissue (MALT)?
- Mucous membranes of GI, urinary, reproductive tracts and airways
- Make up interior lining of membranes that are open to the environment (mouth, nostril, etc)
- Lined with lymphatic tissue
- Any time there is a mucous membrane, there is lymphatic tissue
- Some aggregate (ex. Tonsils)
- 3 sets of tonsils
- Not essential which allow for removal if absolutely necessary