Lymphatic System Flashcards
Lymphatic system is network of lymphatic vessels that withdraws excess ____ from body’s ____, filters through ____ ____, and returns it to bloodstream via _____.
Fluid (lymph)
Interstitial spaces
Lymph nodes
Venous system
Components
Lymphatic vessels Lymph fluid Lymph nodes Lymph tissues Organs
Name the lymph nodes of the UE
Supraclavicular -Axillary -Central -Subscapular -Pectoral -Humeral Cubital
Name the lymph nodes of the LE
Iliac
Inguinal
Popliteal
What are the other 2 lymph nodes (not UE or LE)?
Parasternal
Mesenteric
What are the lymph organs?
Spleen
Tonsils
Thymus
Bone marrow
Flow of lymph
Lymphatic capillaries > lymphatic vessels > large lymphatic ducts (R lymphatic due, thoracic duct) > subclavian veins
Lymphatic vessel contraction occurs by:
- ____ and ___ nerve stimulation
- Contraction of ___ ___.
- ___ and ___ cavity pressure changes during normal breathing
- Mechanical stimulation of ___ tissues
- ___ changes within individual lymph vessels
Autonomic and sensory Adjacent muscles Abdominal and thoracic Dermal Volume
Lymphedema
Chronic disorder characterized by excess accumulation of lymph fluid due to ___ ___ of lymphatic system (____ of lymph flow or ____ of ___ ___).
Mechanical insufficiency
Obstruction
Removal of lymph nodes
Lymphedema
What happens to fluid volume?
What does this result in?
Volume exceeds transport capacity/capability of lymph vessels. Results in swelling of soft tissues of UE/LE.
What is primary lymphedema?
Congenital or hereditary disorder with abnormal lymph node or lymph vessel formation
What is secondary lymphedema?
Acquired insult to lymphatic system
When is secondary lymphedema seen? What are possible causes?
Most common: After surgery breast or cervical cancer
- surgery, including lymph node removal
- tumors, trauma, or infection involving lymphatic system structures
- radiation therapy
- chronic venous insufficiency
- filariasis (parasitic infection of lymph system)
Stages of lymphedema:
Stage 0- at risk, swelling is ___ ___ ___ despite ___ transport capacity of system. Also called the ___ or ___ stage.
Not yet evident
Reduced
Latent
Pre-clinical
Stages of lymphedema:
Stage 1- ____, early accumulation of fluid with visible swelling; ___ edema that resolves with ____; _____ sign is negative
Reversible
Pitting
Elevation
Stemmer’s
Stages of lymphedema:
Stage 2- spontaneously ____; increase in swelling; ___ does not reduce swelling; (+) ____ ____
Irreversible
Elevation
Stemmer’s sign
Stages of lymphedema:
Stage 3- ______; fibrotic deep skinfolds; may change color; skin changes may limit ____
Elephantitis
Mobility
Differential diagnosis is ?
Lipedema
Lipedema: Excessive \_\_\_ \_\_\_ deposition Appearance may be similar to \_\_\_\_\_ Normal function of \_\_\_\_ \_\_\_\_ \_\_\_\_ swelling of extremities Negative \_\_\_ \_\_\_ Seen typically in \_\_\_\_
Subcutaneous fat Lymphedema Lymphatic system Symmetrical Stemmer’s sign Women
What is lymphadenopathy? What causes it?
Enlargement of lymph nodes, with or without tenderness
Usually from infection
Local vs generalized lymphadenopathy
Local is enlargement of nodes in 1 body segment, generalized is enlargement of nodes in 2+ body segments
What is lymphadenitis?
Lymphadenopathy accompanied by signs of inflammation (red, tender)
What is lymphangitis?
What does it appear as?
Acute bacterial (often streptococcus) or viral infection that spreads throughout lymphatic system Red streaks often seen in skin PROXIMAL to infection site
Known risk factors for lymphedema?
Primary
Primary (idiopathic): congenital abnormality— hypoplasia, hyperplasia, aplasia
Known risk factors: secondary (acquired) from known insult to lymphatic system
Most common from what kind of CA and what treatments?
Breast/cervical, lymph node removal or radiation therapy
Volumetric measurements: U/L disease lymphedema is considered present if > ____ % increase compared to unaffected side
10%