lymphatic system Flashcards

1
Q

what are the roles of lymphatic system

A
  • absorb dietary fats and lipid soluble vitamins
  • produce lymphocytes
  • remove overflow of extracellular fluid
  • immune filter for lymph
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2
Q

explain the lymphatic system

A
  • lymph transported in lymph vessels (all over body)
  • filtered through lymph nodes
  • spleen contributes to immune system
  • thymus diffuse lymphoid tissue and bone marrow
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3
Q

what are the 2 primary lymphoid tissues

A

bone marrow and thymus

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4
Q

how is lymph formed

A
  • from excess interstitial fluid originating in capillaryes
  • water solutes and small hydrophilic molecules forced out of capillaries via hydrostatic pressure in capillary bed at arteriole end
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5
Q

what are things you can find in interstitial fluid

A
  • water
  • proteins
  • lipids
  • immune cells
  • maybe cells and bacteria
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6
Q

how many of litres of lymphs is drained daily

A

3-4

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7
Q

what is the swelling of the inferior portion of the thoracic duct known as

A

cisterna chyli (drain everything from below diaphragm)

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8
Q

what are the 6 lymph nodes

A
  • right and left subclavian vein
  • right lymphatic duct
  • thoracic duct
  • superior vena cave
  • cisterna chyli
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9
Q

why are lymph vessels able to drain fluid

A

as they are more permeable than veins

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10
Q

what must happen before fluid from lymph vessels reenter venous system

A
  • filtered by immune system by passing through multiple sets of lymph nodes that contain lymphocytes
  • ## lymphocytes detect microorganisms and remove them so they cant infect body
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11
Q

lymph vessels are also transport system for immune cells

A
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12
Q

what area do the right and left subclavian vein drain

A

right = right upper quadrant
left = left upper and both lower

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13
Q

how are fats absorbed by lymphatic system and what is done with them

A
  • gut epithelial cells absorb and package fats int chylomicrons
  • blind-ending vessels/ lacteals in the intestinal villi take up chylomicrons
  • filter them through lymph nodes
  • into thoracic Duct
  • then into venous system so fat can be transported in safe packages to the body
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14
Q

lymph nodes have multiple AFFERENT (out) vessels but only 1 EFFERENT (in) vessel

A
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15
Q

what landmark can the spleen be found

A

9th - 11th rib in mid axillary line left

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16
Q

what does the spleen do

A

forces RBC to squeeze through tight spaces to make sure cells are healthy
- if cant be squeezed they’re broken down and iron is recycled
- phagocytosis of RBC

17
Q

what are some other functions of spleen

A
  • stores 350 ml of blood approx
  • mount an immune response to blood-born pathogens
  • in fetus, works with liver to make new RBC
18
Q

DEFINE LYMPHANGITIS

A

inflammation of lymph vessel (red on skin surface)

19
Q

define lymphadentis

A

infection of lymph node (swollen)

20
Q

define lymphadenopathy

A

enlargement/disease of lymph node (tumour like growths)

21
Q

define lymphoedema

A

swelling in tissues with interrupted lymph drainage (swelling body parts)

22
Q

what is a sentinel node

A

a lymph node that a lymph travels to first in particular

23
Q

how have sentinel nodes improved breast cancer dealing

A
  • before all lymph nodes would be removed to prevent metasstasis in breast cancer causing lymphedema due to no lymphatic drainage
  • now we now sentinel nodes exist so we can remove those first depending on what lymph area is it
24
Q

how is a sentinel node biopsy carried out

A
  • radioactive tracer, coloured dye or both are injected into breast tissue surrounding tumor
  • injected material migrates to nearby draining lymph node
  • sentinel lymph nodes are identified by radioactive tracer, coloured dye or both and examined for evidence of cancer