lymphatic quiz Flashcards
3 functions of lymphatic system
remove excess interstitial fluid
transport dietary lipids
carry out immune response
order of lymphatic flow
capillaries
vessels
trunks
ducts
back into blood stream
what are the regions of a lymph node and what cells are in each
inner cortex - T cells
outer cortex - B cells
medulla - B cells
what are lacteals
specialized lymph nodes that transport/absorb fat in the GI
what trunk drains the lungs
bronchomediastinal
what is the cell called that can differentiate into any kind of cell and where is it produced
pluripotent
red bone marrow
what cells live inside a lymph node
macrophages
B & T cells
stages of inflammation and what is happening in each
vasodilation - arteries widen allowing increased blood flow, removes toxins, swelling, redness, heat
emigration - neutrophils accumulate to destroy microbes by phagocytosis, monocytes arrive
tissue repair - phagocytes carry out clean up, proliferation and remodeling begin
which antibody activates B cells
IgD
which antibody is breastmilk, mucus
IgA
which antibodies arrive first
IgM
what produces antibodies
B cells/ plasma cells
where are T cells born and where do they mature
born - red bone marrow
mature = thymus
what type of cells are antigen presenting cells
macrophages
B cell
dendritic
5 steps of phagocytosis
chemotaxis
adherence
ingestion
digestion
death
how do natural killer cells kill stuff
granulosin
perforins
granzymes
functions of major histocompatibility complex
identifies each cell in the body where it is foreign or not
MHC 1 - inside cell plasma membranes
MCH II - outside of cell - built into antigen presenting cell
what is structural about lymphatic capillaries
anchoring filaments, more permeable, larger than blood capillaries
difference between right and left lymphatic ducts
right drains the right side of head and upper body
left drains the rest of the body
cisterna chyli
where left thoracic duct originates
what kind of capillaries exist in red bone marrow
highly vascularized sinusoidal
what cells live inside lymph nodes
B&T
how lymph flows through a node
afferent
subcapsular
trabecular
medullary
efferent
hilum
what happens in red and white pulp in spleen
red = cells go to die, platelet storage
white = immune response carried out by B & T cells
where is MALT found and what does it stand for
mucosa associated lymphatic tissue
GI tract, renal, urinary tract
second line defence
antimicrobial
fever
inflammation
function of MCH
place markers or flags on plasma membranes
MHC I
built into plasma membranes of all cells except RBC
INSIDE CELLS
MCH II
built into antigen presenting cells
OUTSIDE CELL
what 3 things activate compliment
antibodies bind antigens
lipids & carbs on microbes
release lectins
3 results of complement system activation
increased phagocytosis
histamine is released
formation of a membrane attack complex
what cells express MCH II and what do not
macrophages, B cells DO
RBCS, T cells DO NOT
T helper cells bind to MHC II to activate B cells
cytotoxic B cells bind MHC 1
antibody mediated are what cells
B
cell mediated are what cells
T cells
macrophages present antigens where
plasma membrane to T cells
dendritic cells present their antigens where
plasma membrane to T cells and B cells
B cells present antigens where
plasma membrane to helper t cells
