Lymph lecture Flashcards
Functions of lymph
Tissue drainage
Return plasma and plasma protein
Part of immunity
Lymphatic vessels
Absorb proteins from tissue fluid
Lymphatic tissues
Eg thymus, spleen, tonsils, bone marrow
How much ISF from extracellular space to venous system a day?
8L
Lymph
Fluid and plasma proteins
Gains lymphocytes in lymphatic capillaries
Fats added in intestine
How is the flow similar to that of veins?
Has valves, muscle contraction, pressure changes and gravity
Is tissue fluid higher or lower in infection and why
Higher as more phagocytosis and oedema due to osmosis
Lymph nodes are primary or secondary lymphoid tissue?
Secondary
Does efferent lymph have more or less antibodies?
More and has been filtered
Lymph node parts
Germinal centre - secondary lymphoid follicles
Lymphocytes
Drainage in limbs
Superficial - superficial veins
Deep - deep veins and arteries
Cavities have superficial or deep arteries?
Deep
Where are lymphatic vessels absent from?
Eyes, CNS, bone, epidermis
What allows superficial ==> deep drainage
Openings in fascia to allow it to get back into circulation
Where are 50% nodes?
Abdomen and pelvis
Preaortic
Infront of aorta, midline, Supply GI and unpaired
Paraaortic
Behind aorta and paired lateral branches to body wall and paired organs
4 pathologies
- Secondary tumour by metastasis
- Infection eg TB
- Inflammatory hyperplasia - enlarged organ
- Primary tumour eg lymphoma hodgkins
Name the 2 lymph ducts
Thoracic duct and right lymphatic duct
Where do these ducts empty?
Jugular/subclavian vein
Which part of the body does the right lymphatic duct drain?
Right upper quadrant including head, neck, upper limb and thorax
Spleen
Largest lymphatic organ and find T and B cells
