Lymph/Hematologic Flashcards

1
Q

What are the components of the hematologic system (3)

A

Plasma (55% of total blood)
Buffy coat (<1% of total blood)
Erythrocytes (45% of total blood)

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2
Q

Erythrocytes aka
Leukocytes aka
Buffy coat is composed of?

A

RBC
WBC
leukocytes and platelets

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3
Q

Serum vs Plasma

A

Plasma is the liquid cell free portion of blood containing fibrinogen

Serum is the liquid part of blood after coagulation so no fibrinogen (removal of clotting cascade)

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4
Q

What is the median hemoglobin count for men vs woman

Around 70% of the amount of iron we need is in

A

M: 15
W: 13

hemoglobin

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5
Q

Your body’s process of making red blood cells

where does it occur

A

erythropoiesis

In both the -
spleen: early development
bone marrow: after birth

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6
Q

Most common signs of hematologic disorders

A

edema - lymphedema, pulmonary edema
congestion
bleeding and bruising

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7
Q

Hemoglobin

A

a protein in red blood cells that allows them to carry oxygen

heme containing iron = red color
globin helps carry and hold oxygen

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7
Q

A lack of enough healthy red blood cells or hemoglobin to carry oxygen to the body’s tissues (overall decrease in hemoglobin)

causes of this?

who is at higher risk?

A

Anemia

trauma/wound
GI cancers
excessive menstruation

woman

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8
Q

Edema

Lymphedema

Lymph

A

swelling caused by too much fluid trapped in the body’s tissues

build up of lymph fluid

clear fluid in the body that contains WBC that collects fluid from tissues and returns them to the bloodstream

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9
Q

Ways to diagnose anemia

what is MCV (mean corpuscular volume)

A

complete blood count
hb test
hct test

Hct x 10 / RBC count

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10
Q

Hemoglobin vs hematocrit

A

Hematocrit is the % of red blood cells in your body
Hemoglobin is a part of your red blood cells

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11
Q

Intrinsic factor

why would a person who is anemic need more than the daily value?

A

A substance secreted by the stomach that enables the body to absorb vitamin b12

Because they do not have enough intrinsic factor they need more than the daily value in order for their body to absorb it

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12
Q

Total body content of iron for men vs woman

heme vs non heme iron

A

M: 4g
W: 2.5g

H: found in animal flesh
N: found in whole grains, nuts, etc

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13
Q

Ferritin
what does it mean when a ferritin test is low

A

blood protein that contains iron
the body’s iron stores is low

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14
Q

Causes of iron deficiency anemia

is it more common in

symptoms

components of PICA (an abnormal desire to eat non food substances)

A

poor nutrition, GI tracts, menstrual, vegans, heart failure, chronic kidney disease

woman

fatigue, headaches, shortness of breath

Ice, starch, paper

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15
Q

Chronic complications of iron deficiency

A

cachexia, renal damage, ketosis, decrease in monocytes or NK cells, heart failure

16
Q

Medical management of iron deficiency anemia

A

-screening and monitoring - endoscopy, colonoscopy,
-ultrasound
-oral supplement
-exercise
-intravenous iron

17
Q

Functions of the lymphatic system

lymph means

A

-part of immunity
-drainage of watery fluid called lymph
-returns fluid back to the heart

clear fluid

18
Q

-Concept of capillary exchange-

osmotic pressure
hydrostatic pressure
what is it

A

-the movement of fluid from the interstitial fluid back into the capillaries
-the pressure that forces fluid out of the capillary
-the exchange of material (nutrients, hormones etc) between the blood and tissues of capillaries

19
Q

3 characteristics of lymphatic capillaries

A

very small
very permeable
held in place by collagen

20
Q

How many L of plasma flow out of capillaries each day
How much is reabsorbed

A

20
17

21
Q

What happens when lymphatic pressure is greater than tissue hydrostatic pressure
What is the order of lymph circulation

A

Lymphedema

Capillaries to vessels to trunks to ducts, ducts dump the lymph into the jugular and subclavian veins

22
Q

A special type of lymph vessel
Where are they found

A

lacteal
small intestine

23
Q

What do lymph nodes contain

Lymphoid organs include

What are peyer’s patches

A

WBC (macrophages/dendritic cells, T cells, NK cells)

Spleen, bone marrow, thymus, tonsils

clusters of lymphoid follicles found in the intestine

24
Q

Of the lymphoid organ the spleen what is white pulp vs red pulp

A

white: lymph node WBC
red: blood, break down and recycle RBC

25
Q

Lymphangitis

Lymphadentitis

Lymphedema

A

inflammation of the lymph vessels

acute infection with inflammation of lymph nodes

absence or obstruction of lymphatic vessels (NOT an infection)

26
Q

Benign/ malignant neoplasm (new growth) of lymph nodes

A

Lymphangioma/Lymphangiosarcoma

27
Q

Diagnosis of lymphedema

clinical complications

medical management

A

ultrasound, MRI/CT

cellulitis, deep vein thrombosis, functional impairments

exercise, nutrition, lymphatic massage

28
Q

Lymphedema functional vs structural impairment

causes of lymphedema

A

S: high protein/lipid, lymph node with or without WBC
F: lymph node deterioration with inflammation

  • hereditary, aplasia, filariasis