Lupus erythematosus

Question 1

Lesion for Chronic cutaneous LE

Answer 1

If chronic, cutaneous lesions only.

Well- demarcated, erythematous, hyperkeratotic plaques with atrophy, follicular plugging, and adherent scale on both cheeks

Question 2

CCLE. Dermatopathology.

Answer 2

Hyperkeratosis, atrophy of the epidermis, follicular plugging, liquefaction degeneration of the basal cel llayer lymphocytic inflammatory infiltrate.Strong PAS reaction. the subepidermal,thickened basement zone.LBT positive in 90% active lesions andn
negative in burned-out (scarred) lesions and in the normal skin, both sun exposed and nonexposed. Low inci- dence o ANAwith titers > 1:16

Question 3

CCLE. % of remission for localized and generalized lesions.

Answer 3

50% localized

< 10% generalized

Question 4

CCLE. % of which will develop into SLE.

Answer 4

1-5%