Acquired Zinc deficiency

Question 1

genetic disorder of zinc absorption. Autosomal recessive trait.
It occurs in infants, bottle-fed with bovine milk

Answer 1

Acrodermatitis enterohepatica

Question 2

Skin and clinical findings.

Answer 2

Patches and plaques of dry, scaly, sharply marginated and brightly red, eczematous dermatitis evolving into vesiculobullous, pustular, erosive, and crusted lesions.
Initially in the perioral and anogenital areas;later,scalp,hands and
feet, flexural regions, and trunk. Fingertips glistening, erythematous, with ssures and secondary paronychia. Perlèche. Lesions become secondarily in ected with Candida albicans, S. aureus.
Impaired wound healing.
■ Diffuse alopecia, graying of hair. Paronychia, nail ridging, and loss of nails.
■ Red, glossy tongue; super cial aphthous-like erosions; secondary oral candidiasis.
■ Photophobia;irritable,depressed mood.
Children with AE whine and cry constantly.Failure of
growth.

Question 3

Lab findings.

Answer 3

Anemia,
lowserumplasma zinc levels;
reduced urinary zinc excretion

Question 4

Management

Answer 4

Dietary or IV supplementation with zinc salts in two to three times the required daily