lung resistances Part 2: static resistances Flashcards

1
Q

static resistance: chest wall

what is the relationship between the force of movement of the chest wall and the force of movement of the lung?

A

the force of movement of the chest wall is the OPPOSITE of the lung

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2
Q

what does the chest wall have a tendency to do and what opposes this

A
  • chest wall has tendency to expand or “spring out”
  • negative pleural pressure opposes this
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3
Q

what percentage of your lung capacity does your chest wall reach if its force to spring open is unopposed?

A

the chest wall will reach 70% of the total lung capacity if unopposed.

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4
Q

what is the name for the resting volume in the lungs when the thorax volume is in equilibrium with the lung volume?

A

functional residual capacity

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5
Q

when does the functional residual capacity occur?

A

when there is no air flow ( at the end of a normal breath )

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6
Q

causes of increased chest wall resistance

what are 5 things that can cause increased chest wall resistance

A

5 things that can cause increased chest wall resistance are:

  • structural abnormality - decreased flexibility/expansion
  • chest trauma
  • loss elasticity
  • blockage of smaller respiratory passages with mucus or fluid
  • raised abdominal pressure
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7
Q

what are 3 examples of structural abnormality, causing increased resistance of the chest wall

A
  • deformities of thorax
  • ossification of the costal cartilage
  • paralysis of intercostal muscles
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8
Q

what are 3 examples of chest trauma that cause increased resistance of the chest wall

A
  • paralysis
  • strain
  • pain
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9
Q

what is an example of loss of elasticity of the lungs, causing increased resistance of the chest wall

A
  • burns
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10
Q

what are 3 examples of raised abdominal pressure that can cause increased chest wall resistance?

A
  • obesity
  • pregnancy
  • scoliosis
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11
Q

static resistance: lungs

what is elastic recoil, why do lungs have natural tendency to collapse and what holds the lungs open and what establishes this?

A
  • tendency of an elastic structure to oppose stretching
  • lungs have tendency to collapse because of elastic recoil
  • held open by intrapleural pressure established by lymphatic pumping of fluid
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12
Q

what 2 things can cause lung collapse, and what are their overall proportions in causing collapse?

A
  • elastin and collagen in lung tissues (1/3 of collapses)
  • surface tension abnormalities ( 2/3 of collapses)
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13
Q

what 2 fibres are interwoven in the lung parenchyma

A
  • elastic fibres
  • collagen fibres
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14
Q

what are elastin fibres for?

A

to help expand the lungs and allow them to return to their normal shape due their elastic properties

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15
Q

surface tension

what do small alveoli have a greater tendency to do and why?

A
  • small alveoli (smaller radius) have a greater tendency to collapse and empty its air into connected larger alveoli as smaller alveoli are unstable
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16
Q

what are collagen fibres for?

A

to stiffen the lung tissue once they have expanded

17
Q

what does reduction in ST forces allow for?

A

allows for interdependence and stability

18
Q

why do smaller alveoli need a larger inflating pressure?

A

because they have a larger collapsing pressure

19
Q

what is the equation linking inflating pressure, collapsing pressure and radius?

A

P = 4ST/f

where:

  • P = inflating pressure
  • 4ST = collapsing pressure
  • f = radius
20
Q

what is surfactant

A

a secretory product that is composed of lipids & proteins that lowers the surface tension at the air-liquid interface to prevent alveolar collapse

21
Q

when is surfactant synthesised in babies?

A

surfactant is synthesised between weeks 24-28 in babies

22
Q

what synthesises surfactant?

A

Type II pneumocytes

23
Q

benefits of surfactant

what 4 things does surfactant do?

A
  • makes the transmural pressure needed to expand the lungs 3x smaller
  • keeps alveoli dry
  • maximises area for ventilation and perfusion
  • maintains alveolar interdependence by acting as additional splints to keep alveoli open
24
Q

how does surfactant keep the alveoli dry?

A

surfactant keeps the alveoli dry by lowering the inwardly directed pressure that draws water into the alveoli

25
Q

how does surfactant maximise area for ventilation and perfusion

A

surfactant maximises area for ventilation and perfusion by reducing surface tension for small alveoli compared to larger alveoli as surfactant molecules crowd into the smaller space.

26
Q

how does surfactant maintain alveolar interdependence

A

surfactant maintains alveolar interdependence by aiding fibrous tissue in septal walls between alevoli of different sizes, thus acting as an additional splint

27
Q

disorderes influencing surface tension

what 3 disorders can alter/destroy surfactant

A
  • Neonatal respiratory distress syndrome caused by prematurity
  • adult respiratory distress syndrome
  • oxygen toxicity
28
Q

what is the most prevalent component in surfactant?

A

dipalmitoyl phosphatidylcholine (DPPC)