Lung Pathology VI Flashcards
pulmonary hamartoma
popcorn calcification
has cartilage
benign, resectable
bronchioalveolar carcinoma
carcinoma in situ**
non-small-cell lung carcinomas
squamous cell
adenocarcinoma
large cell carcinomas
leading cause of cancer deaths
lung
cancer with smoking
lung, oral, pharyngeal, esophageal, pancreatic, cervical, renal, bladder
risk of lung cancer
determined by number of cigs smoked
4-aminobiphenyl 2 naphthylamine
bladder cancer from tobacco smoke
phenol
tumor promotion
polycyclic aromatic hydrocarbons
carcinogenesis in lungs and larynx
nitrosmaine
carcinogenesis
non-smoking female lung cancer
adenocarcinoma
peripheral location
squamous cell lung cancer
smoker - central location
-near hilum
EGFR or KRAS
in adenocarcinoma
RB and BCL2
in small cell carcinoma
strong association
p16 and P53
squamous cell carcinoma
chest pain, hemoptysis, weight loss
lung cancer
also pneumonia, abscess, lobar collapse, emphysema
pancoast tumor
apical lung tumor with pain in distribution of ulnar nerve and horner syndrome
horner syndrome
in pancoast tumor
enopthalmos, ptosis, miosis, and anhidrosis**
PTHrp
hypercalcemia
in squamous cell carcinoma
hypercalcemia with no metastasis
squamous cell carcinoma