ENT Pathology I Flashcards

1
Q

schneiderian mucosa

A

line nasal cavity and rhinonasal sinuses

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2
Q

sinonasal respiratory mucosa

A
  • ciliated pseudostratified columnar cells
  • mucin-containing goblet cells
  • basal cells
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3
Q

green mucus

A

bacterial

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4
Q

acute rhinitis

A

will go away in week

may progress - pharyngitis, sinusitis, otitis media

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5
Q

coryza

A

inflammation of mucous membrane of nose

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6
Q

majority of acute rhintis

A

colds - viruses

rhinoviruses
-picornaviruses, ss-RNA, enterovirus

also adenovirus, echovirus, coronarvirus, parainfluenza, RSV

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7
Q

RAST testing

A

of allergens

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8
Q

allergic rhintis

A

hay fever

-rhinorrhea, sneezing, congestions, itching

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9
Q

seasonal hay fever

A

particular time of year

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10
Q

perennial hay fever

A

all year round

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11
Q

episodic hay fever

A

bouts at irregular intervals

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12
Q

hay fever

A

type I hypersensitivity

  • IgE mediated
  • Th2 response
  • early - mast cells/histamine
  • late - eosinophils
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13
Q

most common eosionphilia in US

A

allergies

other nations - parasites

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14
Q

chronic rhintis

A

longer than 1 months of symptoms

common with polyps or deviated septum

typical onset - after age 20

Sx
1 sneezing
2 rhinorrhea
3 nasal congestion
4 postnasal drainage
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15
Q

nasal polyps

A

with recurrent rhintis
-may cause obstruction

edematous tissue with eosinophils

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16
Q

maxillary sinus

A

can get infection through resp tract AND the mouth

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17
Q

sinusitis

A

inflammation of sinus with associated nasal mucosa often

aka rhinosinusitis

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18
Q

acute rhinosinusitis

A

< 1 month

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19
Q

subacute rhinosinusitis

A

1-3 months

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20
Q

chronic rhinosinusitis

A

> 3 months

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21
Q

mucocele of sinus

A

mucus blockage of sinus

in rhinosinusitis

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22
Q

facial pain, pressure, congestions

A

sinusitis

acute - has fever
-may spread to bone - osteomyelitis

23
Q

acute viral infectious sinusitis

A

clears 7 days or less

-rhinovirus, influenzavirus, parainfluenzavirus

24
Q

acute bacterial infectious sinusitis

A

complication of viral sometimes

streptococcus pneumoniae
haem influenza
moraxella catarrhalis (kids)

Sx more than 7 days**
Sx get worse**
associated with dental disease**

25
Q

ASA triad**

A

chronic rhinosinusitis, nasal polyp, severe bronchial asthma

allergic rxn to aspirin

26
Q

majority of chronic obstructive sinusitis

A

obstructive

27
Q

kartagener syndrome

A

immotile cilia
-situs inversus possible

can lead to chronic obstructive sinusitis

28
Q

diabetics

A

high glucose - fungal infections in chronic obstructive sinusitis

29
Q

bacteria in chronic obstructive sinusitis

A

staph aureus majority

30
Q

allergic mucus

A

recurrent sinusitis with lots eosinos with no organisms present

31
Q

charcot leyden crystals

A

eosinophil mucus

32
Q

allergic fungal sinusitis

A

recurrent sinusitis - with eosino mucus with fungi

33
Q

fungal ball

A

mycetoma

fungal organisms, scant mucus, little inflammation

see mass lesion by Xray in sinus cavity

34
Q

invasive fungal sinusitis

A

severe sinusitis
-neuro deficit

fungal organisms INVADE tissues and vessels

35
Q

wegeners granulomatosis

A

granulomatosis with polyangiitis

c-ANCA
PR53

36
Q

cocaine

A

vasoconstrictor
-perforated septum

necrotizing to upper airways

37
Q

diabetic, chronic sinusitis, swelling around face, HAs

A

rhinocerebral mucormycosis

in immunocompromised
-mucor - does not pick up silver stain

38
Q

hansen disease

A

lepromatous leprosy

mycobacterium leprosy

can lead to necrotizing lesions of upper airways

39
Q

NK-T cell lymphoma

A

malignant lymphocytes
-go to wall of vessel

lumen compromised

midline - nose to testis

40
Q

broad hyphae in diabetic

A

mucor

rhinocerebral mucormycosis

mucor - likes iron - diabetics hav higher iron content

41
Q

18yo M, unilateral nasal obstruction, epistaxis, swelling of face, eye, cheek

A

nasopharyngeal angiofibroma

benign

highly vascularized

posterolateral wall

42
Q

nasopharyngeal angiofibroma

A
posterolateral
highly vascularized
benign
young males
epistaxis

Tx - surgical resection - presurgical embolization of vessels

43
Q

exophytic schneiderian papilloma

A

septal**
squamous

majority

associated with HPV

Tx - resection

20-50yo M

fugiform villous formation

44
Q

schneiderian benign neoplasms

A

nasal cavity and septum

45
Q

inverted schneiderian papilloma

A

lateral**
-near middle turbinate
squamous

harder to resect - can become malignant

associated with HPV

40-70yo M

squamous epithelium invaginates into lining

46
Q

oncocytic schneiderian papilloma

A

lateral**
cylindrical/columnar

> 50yo

no HPV associated

abundant bright pink cytoplasm - oncocytic

some to invasive carcinoma

47
Q

squamous papilloma

A

wart in nose

  • verruca vulgaris
  • anteior in nose toward nares

more common than schneiderian tumors

48
Q

esthesioneuroblastoma

A

olfactory neuroblastoma
-from neuroendocrine cells

top of nose

see neuro markers

5 years survival 40-90%

Tx - surgery

49
Q

small blue cell tumor

A

olfactory neuroblastoma

50
Q

SYP, NSE, chronogrannin, CD55/57

A

markers for neuroendocrine tumors

synaptophysin
neuron specific enolase

51
Q

tumor top of nose in back, small blue cells, neuro markers

A

esthesioneuroblastoma

52
Q

nasopharynx

A

non-keratinizing squamous

and resp epithelium

53
Q

oropharynx and laryngopharynx

A

100% non-keratinizing squamous