Loops And Pathways Flashcards
The subthalamic nucleus sends _________ to the GPi
Glutamate
The GPi sends _________ to the motor thalamus
GABA
The motor/premotor area of the cortex sends ________ to the subthalamic nucleus or putamen
Glutamate
It sends glutamate to putamen in GO pathway and NO GO
It sends glutamate to subthalamic nucleus in STOP
The putamen sends ______________ to the GPi or GPe depending on the pathway
GABA
The GPe sends __________ to the subthalamic nucleus
GABA
But when inhibited by the putamen it sends less GABA which disinhibits the GPi
Goal Directed behavior pathway
_________ prefrontal cortex -> ____________ -> GPi -> Thalamus
Lateral
Head of Caudate
Just remember: He’s goal directed with a good head on his shoulders :) Head of the caudate. Also it’s involved in the social loop because to be socially successful you have to have a good head on your shoulders. The head of the caudate is NOT in the emotional loop because being too emotional is the opposite of that.
Goal Directed behavior loop
Lateral prefrontal cortex -> head of caudate -> _________ -> ___________
GPi
Thalamus
Remember it takes discipline to accomplish your goals! So thats why the GPi is included (it inhibits unwanted behavior)
Which loop can have deficits of inattention, poor concentration, short term memory?
Goal directed behavior
Social Behavior loop
_____ prefrontal cortex -> __________ -> substantia nigra reticularis -> thalamus
Remember that being social makes you hapy so thats why this loop includes the substantia nigra (dopamine)
Ventral
Head of caudate
Social Behavior Loop
Ventral prefrontal cortex -> Head of caudate -> _____________ -> thalamus
Substantia Nigra Reticularis
social behavior gives you dopamine!
Deficits of what loop can lead to impulsivity, indifference, and violence?
Social Behavior Loop
Emotional Loop
______ prefrontal cortex -> ventral striatum -> thalamus
Medial
How I will remember: If you’re stuck in an emotional loop, you probably need to vent (ventral striatum)
Emotional Loop
Medial prefrontal cortex -> ________________ -> Thalamus
Ventral Striatum
Deficits of what loop lead to impaired reward seeking behavior/addiciton
Emotional Loop
A _______________ stroke causes depression and dulling of emotion
L basal ganglia,
Bc it damages the emotional loop