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Lobular proliferation of sebocytes.
Frothy or bubbly cytoplasm d/t lipid vesicles
Sebaceous Adenomas
fishlike scales
Ichthyosis
Erosions and hemorrhagic crusting of the lips, oral mucosa, conjunctiva, urethra and anogenital regions in kids
Stevens Johnson Syndrome
type of Erythema Multiforme
- younf F’s
- Asymptomatic or tender, may increase and decrease slightly over time.
- Some pts had antecedent trauma
Benign Fibrous Histiocytoma (dermatofibroma)
+ other tumors (medulloblastomas and ovarian fibromas).
+ Odontogenic keratocysts.
+ Pits of the palms & soles.
+ Developmental anomalies
Nevoid Basal Cell Carcinoma (NBCC) AKA: basal cell nevus, Gorlin syndrome.
severe acne along sinus tract and dermal scarring
acne coglobata
Appendage tumor predominantly seen on the hands and soles where sweat glands are numerous.
eccrine poroma
Rodent ulcer:
BCC
=ulceration of advanced lesions that show extensive local invasion. Someone comes in with a cut that isn’t healing.
macrocephaly, trichelemmomas (benign tumors of hair follicle), and papillomatous papules (white papules w a smooth surface in the mouth
cowden synd
Soft, flesh colored tumors attached via a slender fibrovascular stalk.
Fibroepithelial Polyp (acrochordon, squamous papilloma, skin tag)
Sudden appearance of multiple seborrheic keratoses and paraneoplastic syndrome w GI carcinoma
Leser-trélat sign (from seborrheic keratosis)
o Affects skin of elbows, knees, scalp, lumbosacral areas, intergluteal cleft and glans penis mostly
o Lesions are pink-salmon colored plaques covered by loosely adhering silver-white scales.
psoriasis
Urticaria and vesicles associated w scarring.
Exacerbated by sunlight.
porphyria
- Invagination and cystic expansion of epidermis or a hair follicle.
- Filled with keratinaceous material
Epithelial or Follicular Inclusion Cyst (Wen)
Factor XIIIa (+) dermal dendritic cells.
Benign Fibrous Histiocytoma (dermatofibroma)
Multiple small lesions on the face of people of color.
Dermatosis papulosa nigra (type of seborrheic keratosis
Dermatographism
systemic mastocytosis
o Area of derma edema resembling a bee hive that occurs d/t localized stroking of apparently normal skin with a pointed instrument.
hairless patches of skin with mild erythema, crust formation and scaling
tinea capitis
Darier Sign
systemic mastocytosis
o Localized area of dermal edema and erythema (wheal) that occurs when lesional skin is rubbed.
multiple, small, tan papules near the lower eyelids.
Syringoma
o Early: eczema like lesions
o Eventually multiple, large, red-brown nodules indicate systemic dz.
Mycosis Fungoides (Cutaneous T-cell Loma (CTCL)
Fibroepithelial polyps and perifollicular mesenchymal tumors
Birt-hogg-dubé syndrome
Yellow-brown nail changes with pitting, dimpling and separation of nail plate from underlying bed (onycholysis), thickening and crumbling.
psoriaisis
scalp, foreheadglabella, EAC, retroauricular area, nasolabial folds, presternal area:
o Macules & papules on an erythematous yellow, greasy base.
o Often with scaling and crusting
Seborrheic Dermatitis