27 assoc Flashcards
URI
bells palsy
DM
bells palsy
an influenze like illness that recovered from
Guillain-Barre Syndrome
C. Jejuni, CMV, EBV, M. Pneumoniae; vaccination, Zika in the pacific islands
Guillain-Barre Syndrome
RA, sjogrens, SLE
sensory or sensorimotor peripheral neuropathy
vasculitis
peripheral neuropathy
Acute peripheral neuropathy assoc w prominent bulbar and respiratory muscle dysfunction.
d/t diptheria
neurogenic bladder
neuropathy from uremia
hypothyroidism causes –>
Compression mononeuropathies (carpal tunnel) or distal symmetric predominantly sensory polyneuropathy.
hyperthyroidism causes–>
Neuropathy resembling Guillain-Barre syndrome
paraneoplastic sensorimotor neuropathy usu caused by:
small cell (neuroendocrine) lung CA
tissue edema, pregnancy, inflam. Arthritis, hypothyroidism, amyloidosis, acromegaly, DM, repetitive wrist motions
carpal tunnel synd
thymoma/thymic hyperplasia
myasthenia gravis
paraneoplastyc synd from small cell (neuroendocrine) lung CA cuases
Lambert-Eaton Myasthenic Syndrome
Anti-Mi2 Abs
Vs. Helicase implicated for nucleosome remodeling.
• Assoc w prominent Gottron papules and heliotrope rash in dermatomyositis
Anti-Jo1 Abs:
Vs. Histidyl tRNA transferase synthetase.
• Assoc w interstitial lung dz, nonerosive arthritis, skin rash (‘mechanics hands’) in dermatomyositis
Anti-P255/P140 Abs:
Vs. Several transcriptional regulators.
• Assoc w paraneoplastic & juvenile cases in dermatomyositis
statins
Toxic Myopathies (progressive m weakness)
Chloroquinolone & hydroxychloroquine
Toxic Myopathies (progressive m weakness)
