26 morph Flashcards
bone lacks medullary canal = no hematopoetic marrow
osteopetrosis
erlenmeyer flask deformity
osteopetrosis
neural foramina small
osteopetrosis
nml bine, but decreased quantity of trabecular bone
osteoporosis
Mosaic pattern of lamellar bone. ‘Jigsaw puzzlelike’ d/t unusually prominent cement lines orienting lamellar bone
sclerotic phase Paget Disease (osteitis deformans)
‘Cotton wool’ appearance.
Paget Disease (osteitis deformans)
wedge shaped empty lacunae that are surrounded by ruptured adipocytes, which can have assoc fat saponification (may remain for life).
Osteonecrosis (avascular necrosis)
tissue paper cells
goucher dis: Osteonecrosis (avascular necrosis)
Involucrum: .
o : . (pic)
o : .
pyogenic osteomelitis
=subperiosteal new bone encasing the inflamm focus
Brodie abscess
pyogenic osteomelitis
=small, walled off intracortical abscess
gummas
Skeletal Syphilis (congenital)
well circumscribed nodules of translucent cortical, interlacing woven bone (nidus) rimmed by osteoblasts; surrounded by vasc and loose CT
osteoid osteoma and osteobalstoma
formation of bone by tumor cells*; fine, lace-like pattern or may be deposited in broad sheets
osteosarcoma
sessile/peduncleated solitar, cartilage cap mass; cortex of the stalk merges with the cortex of the host bone so that the 2 medullary cavities are continuous.
Osteochondroma (exostosis)
multiple cartilaginous tumors of hands and feet
chondroma
Translucent gray-blue tumors, < 3cm with limited growth potential.
Well-circumscribed nodules of benign hyaline cartilage.
Peripheral portion of the nodules may undergo enchondral ossification and the center can calcify and infarct.
chondroma
spindle cell hemangioma
maffucci synd
malig tumor producing cartilage on the axial skeleton (pelvis, shoulder, ribs)
chondrosarcoma
Transluscent cartilage w gelatinous or myxoid matrix (may ooze from cut surfaces).
Spotty calcifications.
chondrosarcoma
homer-Wright rosettes
Ewing Sarcoma Family Tumors (ESFT) (including PNET)
tumor rich in glycogen, hem, necrosis
Ewing Sarcoma Family Tumors (ESFT) (including PNET)
onion-skinning
Ewing Sarcoma Family Tumors (ESFT) (including PNET)
expansile lesion w well defined margins at metaphysis of long bones
Aneurysmal Bone Cyst (ABC)
.5cm on metaphysis of distal femur, prosimal tibia, storiform (pinwheel) pattern and foamy mfs clustered in giant cells
Fibrous Cortical Defect (metaphyseal fibrous defects) and non-ossifying fibromas