Liver & Biliary System Pathology

Question 1

What are the 3 main functions of the liver?

Answer 1

Storage, Synthesis and metabolism(detoxification)

Question 2

Name 3 general symptoms of liver disease

Answer 2

Nausea, fatigue, vomiting, anorexia, abdominal pain

Question 3

What are the 3 features of cirrhosis?

Answer 3

Fibrosis, hepatocyte necrosis and nodules

Question 4

Is cirrhosis reversible or irreversible?

Answer 4

Irreversible

Question 5

By which 3 mechanisms can alcohol affect the liver?

Answer 5

Fatty change, Alcoholic hepatitis then cirrhosis

Question 6

Does Hep B & C have a vaccine or cure?

Answer 6

Hep B = vaccine, no cure

Hep c = no vaccine, cure

Question 7

During acute infection is hep B & C symptomatic?

Answer 7

Hep B = symptomatic, Hep C = Asymptomatic

Question 8

What is Hereditary Haemochromatosis?

Answer 8

Increased absorption of iron and deposition in liver

Question 9

What is Wilsons Disease?

Answer 9

Reduced secretion of copper that accumulates in tissues

Question 10

Where are the most important sites of varices in portal hypertension?

Answer 10

Oesophageal, Anorectal, Umbilical

Question 11

What is Biliary Colic?

Answer 11

Temporary obstruction of a gallstone in the cystic duct, usually a few hours after eating

Question 12

What is acute cholecystitis?

Answer 12

Impaction of a stone in the cystic duct, murphys sign positive

Question 13

What is acute cholangitis?

Answer 13

Infection of the biliary tree, charcots triad. Usually caused by impacted CBD stone.