Large Bowel & IBD Flashcards
How is the transverse colon different to the ascending and descending colon?
It has its own mesentery and is intraperitoneal
What is the marginal artery?
An artery through the large bowel formed by anastomoses from branches of superior and inferior mesenteric arteries
Where does the foregut drain into?
Splenic vein and portal vein (no celiac trunk vein)
Where does blood from the rectum drain?
Upper 3rd into superior rectal vein, lower 2/3rds into systemic venous system bypassing the liver
What is the teniae coli?
Three distinct bands of longitudinal muscle in the large intestine
What are Haustra?
Sacculations formed by contraction of the Teniae coli
Which channel aids water absorption in the colon?
ENac
Crohns vs Ulcerative Colitis
Crohns = affect anywhere in GI tract, transmural, skip lesions UC = Begins in rectum, continuous pattern of mucosal inflammation
Briefly describe the gross pathology of Crohns
Mucosal oedema, discrete superficial ulcers, deep ulcers. Cobblestone appearence.
What is the microscopic pathology that can indicate Crohns?
Granuloma formation
What investigations can be carried put for Crohns?
Bloods and CT/MRI scan to show bowel wall thickening or obstruction
What is the microscopic pathology that can indicate UC?
Crypt abscesses and distortion , reduced number of goblet cells
Briefly describe the gross pathology of UC
Pseudopolyps and loss of haustra
Does Crohns or UC have perianal disease?
Crohns
What is the “String sign of Kantour”?
Long strictures that can be found in Crohns from a barium follow through
