GI Jaundice & LFTs Flashcards
1
Q
What happens to Bilirubin in the liver?
A
Conjugated to make it water soluble
2
Q
What causes pre-hepatic jaundice?
A
Too much haem
3
Q
What causes hepatic jaundice?
A
Reduced hepatocyte function
4
Q
What post-hepatic jaundice?
A
Obstructive causes
5
Q
Why can post-hepatic jaundice cause dark urine and pale stools?
A
Conjugated bilirubin is water-soluble so most of it is excreted in the urine
6
Q
Which LFT is most specific to the liver?
A
ALT, rises more in acute liver damage
7
Q
What may cause ALT to increase?
A
Bile duct obstruction and bone turnover.
