Liver Flashcards

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1
Q

What are hepatcytes

A

Liver cells

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2
Q

Function of sinusoids

A
facilitate exchange (uptake and secretion) between hepatocytes
and blood
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3
Q

Function of Kupffer cells

A

mononuclear
phagocyte system which patrol the space of Disse
between hepatocytes and blood

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4
Q

75% of blood flow to the liver is by which vessel

A

Portal vein

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5
Q

25% of blood flow to the liver is by which vessel

A

Hepatic artery

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6
Q

Components of Portal triad

A

Hepatic artery, portal vein and bile duct

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7
Q

Blood flow out of the liver is by which vessel

A

Hepatic vein

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8
Q

Found at apical surface of hepatocytes

A

Canaliculi

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9
Q

Found at basal surface of hepatocytes

A

Microvilli

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10
Q

Bile is secreted into which structure in the liver

A

Bile canaliculi

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11
Q

The components of the portal triad leaves the liver through what structure

A

Hapatic hilum

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12
Q

The heptic artery and portal vein drain into what structure

A

Central vein

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13
Q

Bile flows from what structure to what structure in the liver

A

From central vein to bile duct

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14
Q

Describe a classic hepatic lobule

A

a hexagonal structure with a portal tract at each corner

of the hexagon and a central vein in the center of the hexagon

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15
Q

Describe a portal lobule

A

a triangular structure with a central vein at each corner and a
portal tract in the center

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16
Q

Describe a hepatic acinus

A

a roughly elliptical structure with portal

tracts at the 2 furthest poles and 2 central veins at the 2 closest edges

17
Q

In which hepatic structure does bile flow towards the center

A

Portal lobule

18
Q

Which zone receives the most oxygen

A

Zone 1

19
Q

Which zone receives the least oxygen

A

Zone 3

20
Q

What occurs in zone 1

A

Synthesis of glycogen and plasma proteins

21
Q

What occurs in zone 3

A

Detoxification, lipid, drug, alcohol metabolism

22
Q

Function of Ito/Stellate cells

A

Storage of Vitamin A (fat soluble vitamin) and secretion of collagen type I during damage to liver

23
Q

Which 2 cell types are found in the space of Disse

A

Ito cells and Kupffer cells