Bile Flashcards
What is the starting form of cholic acid and chenodeoxycholic acid
Cholesterol
What are the primary bile acids
cholic acid and chenodeoxycholic acid
What is the process by which lipid soluble bile acids are converted to water soluble
Congugation
What are lipid soluble bile acids conjugated with
Glycine
Why are bile acids called bile salts
Because they exist as salts of cations
Which organ actively secretes bile
Liver
By what processes are secondary bile acids formed
Deconjugation and dehydroxylation
What are micelles
Form when bile become concentrated and are water soluble with a lipid core
Importance of micelles
Transportation of lipids through aqueous media in the gall bladder and intestines
What is Enterohepatic circulation
Process by which bile is reabsorbed into the ileum and eventually returned to the liver
Steps in enterohepatic circulation
Absorption in ileum, to portal vein, to liver, to cystic duct (gall bladder), to the duodenum and back to the ileum
Only part of the GIT that can absorb bile
Distal Ileum
Importance of concentration of bile in portal vein
Concentration of bile in the portal vein directly relates to bile made by liver
Consequence of an ileal resection
No reabsorption of bile, means not even production of mile which means malabsorption of fats, so fats will be in stool (steatorrhea)
Causes of gall stones
Over absorption of water
Over absorption of bile
Too much cholesterol
Epithelial inflammation
