Gluconeogenesis

Question 1

What is the purpose of gluconeogenesis

Answer 1

To maintain blood glucose level

Question 2

Gluconeogenesis begins after the level of what drops?/

Answer 2

Glycogen

Question 3

Three main substrates of gluconeogenesis

Answer 3

glycerol-3-phosphate
lactate
Gluconeogenic amino acids

Question 4

Which two amino acids are no gluconeogenic

Answer 4

Lysine and leucine

Question 5

Which product from other metabolic pathways cannot be converted to glucose in humans by gluconeogenesis

Answer 5

Acetyl coA

Question 6

Does insulin increase or decrease gluconeogenesis

Answer 6

decrease

Question 7

Does glucagon increase or decrease gluconeogenesis

Answer 7

increase

Question 8

After approximately how many hours are glycogen stored depleted

Answer 8

12-18

Question 9

Substances that positively affect glycolysis increase or decrease gluconeogenesis

Answer 9

Decrease

Question 10

What two substances are converted to pyruvate during gluconeogenesis

Answer 10

Alanine and lactate

Question 11

Which enzyme is responsible for converting alanine to pyruvate during gluconeogenesis

Answer 11

Alanine amino transferase

Question 12

Which enzyme is responsible for converting lactate to pyruvate during gluconeogenesis

Answer 12

Lactate dehydrogenase

Question 13

Which enzyme is responsible for converting G3P to DHAP during gluconeogenesis

Answer 13

G3P dehydrogenase

Question 14

What are the 4 important enzymes that catalyze irreversible steps during gluconeogenesis

Answer 14

Pyruvate carboxylase,
phosphoenolpyruvate carboxylase,
fructose-1,6-bisphosphatase
Glucose-6-phosphatase

Question 15

Which of the 4 important enzymes during gluconeogenesis is only found in the liver and therefore prevents muscles from breaking down glycogen

Answer 15

Glucose-6-phosphatase