Lipoglycopeptides Flashcards
1
Q
What are lipoglycopeptides?
A
- Dalbavancin: only drug on chart
- Telavancin
- Oritavancin
2
Q
What is the route for Dalbavancin?
A
IV
3
Q
What is the MOA for Dalbavancin?
A
Inhibition of transglycosylation by binding to D-ala-D-ala
4
Q
What gram positive bacteria is Dalbavancin effective against?
A
- MRSA
- MSSA
- Strep
- coagulase negative staph
5
Q
What gram negative bacteria is Dalbavancin effective against?
A
NONE!
6
Q
What anaerobic bacteria is Dalbavancin effective against?
A
- Clostridium perfingens
- C. dificile
- proprionibacterium acnes
- Peptostrepococcus
7
Q
What are the clinical uses for Dalbavancin?
A
Skin and soft tissue infection
8
Q
What are the SE for Dalbavacin?
A
- Metallic taste
- N/V
- HA
- Nephrotoxicity
- Teratogenic
