Cyclic Lipopeptide Flashcards by Sarah Moore | Brainscape

Q

What are cyclic lipopeptides?

A

Daptomycin

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Q

What is the route of administration for Daptomycin?

A

Injection

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Q

What is the MOA for daptomycin?

A

insertion into the gram-positive cell membrane causing depolarization and ultimate cell death

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Q

What gram positive bacteria is daptomycin effective against?

A

NSSA
MRSA
Coagulase negative staph
enterococci
VRE
Streptococci

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Q

What gram Negative bacteria is daptomycin effective against?

A

NONE!

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Q

What anaerobic bacteria is daptomycin effective against?

A

NONE!

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Q

What are the clinical uses for Daptomycin?

A

Alternative for Vancomycin

2. VRE infection

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Q

What are the SE for Daptomycin?

A

Myalgias
Rhabdomyolysis: monitor CK MM
Eosinophilic pneumonia: rare

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