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Biochem Prelim 2nd Sem > Lipd Metabolism Fat Absorption > Flashcards

Lipd Metabolism Fat Absorption Flashcards

0
Q

Absorption of long chain fatty acid and 2 monoacylglycerol

A 
Longchain FA + 2 MAG combine with bile salts
Bile salt micelle
Release FA and 2MAG in intestinal cells
Absorbed in intestinal cells
Then FA and 2 MAG react with each other
Form long chain TAG
Reacts to apoprotein (chylomicrons)
Absorbed in lymphatic circulation to systemic circulation
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1
Q

Absorption of short and medium chain FA

A

Readily absorbed

Portal circulation to liver

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2
Q

Absorbed by the lymphatic circulation to systemic circulation

A

Chylomicrons

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3
Q

Bring up long chain FA and 2 MAG to intestinal cell

A

Bile salts micelles

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4
Q

Appoprotein, a protein molecule and form lipoprotein molecule called

A

Chylomicrons

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5
Q

Obstruction of the common bile duct.
Bike doesn’t reach the intestine
Increase amount of digested but unabsorbed fats

A

Steatorrhea due to bile deficiency

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6
Q

Gives color to stool

A

Stercobilin

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7
Q

Saan galing ang stercobilin

A

Sa stercobilinogen na content din ng bile aside from bile salts

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8
Q

Kung ang obstruction ay above the ampula of vater, digeted parin ang fats

A

2 hepatic duct
Cystic duct
Common bile duct

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9
Q

Increase amount of undigested and unabsorbed fats in the feces

A

Steatorrhea due to pancreatic juice deficiency

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10
Q

Steatorrhea due to pancreatic juice deficiency

Cause

A

Chronic pancreatitis
Pancreatic carcinoma
Obstruction on the ampulla of vater

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11
Q

Steatorrhea due to pancreatic juice deficiency

Color of stool

A

Normal color, no obstruction in the common bile duct

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12
Q

Increased amount of digested but unabsorbed fats in the feces
Normal stool color

A

Steatorrhea due to abnormal intestinal mucosa

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13
Q

Steatorrhea due to abnormal intestinal mucosa

Causes

A

Celiac disease due to hypersensitivity reactions

Prolong intake of gluten that destroys the intestinal mucosa

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14
Q

Biosynthesis of non essential fatty acids

A

Lipogenesis

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15
Q

Fats synthesized in the body

A

Non essential fatty acids

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16
Q

Fats that cannot synthesized of the body

A

Essential fatty acids

17
Q

two kinds of essential fatty acids

A

Alpha linoleic acid

Linoleic acid

18
Q

Alpha linoleic acid

A

Omega 3 fatty acid

19
Q

Linoleic acid

A

Omega 6 fatty acid

20
Q

Difference between saturated and unsaturated fats

A

Saturated- bad

Unsaturated - good

21
Q

Example of monounsaturated fatty acids

A

Palmitoleic acid

Oleic acid

22
Q

Types of lipogenic pathway

A

Extramitochondrial lipogenesis
Microsomal lipogenesis
Mitochondrial lipogenesis

23
Q

Most active and important lipogenic pathway

A

Extramitochondrial lipogenesis

24
Q

Extramitochondrial lipogenesis location

A

Cytosol

25
Q

Microsomal lipogenesis location

A

Smooth ER

26
Q

Mitochondrial lipogenesis location

A

Mitochondria

27
Q

Extra mitochondrial lipogenesis

Aka

A

Lynens pathway

28
Q

Extra mitochondrial lipogenesis

Substrate

A

Acetyl CoA

Non fatty acid

29
Q

Extra mitochondrial lipogenesis

End product

A

Palmitic acid

30
Q

Extra mitochondrial lipogenesis

Donor of two carbons

A

Malonyl CoA

31
Q

Extra mitochondrial lipogenesis

Anchoring protein

A

Acyl carrier protein

32
Q

Denovo synthesis of fatty acids

A

EML

33
Q

Microsomal and mitochondrial lipogenesis

Type

A

Elongation pathway

34
Q

Microsomal and mitochondrial lipogenesis

Substrate

A

Medium to long chain fatty acids

35
Q

Microsomal and mitochondrial lipogenesis

End product

A

Longer chain FA

36
Q

Microsomal and mitochondrial lipogenesis

Donor of 2 carbons

A

Mitochondrial- acetyl CoA

Microsomal - malonyl CoA

37
Q

Microsomal and mitochondrial lipogenesis

Anchoring protein

A

Co Enzyme A

38
Q

16 carbon atoms

A

Palmitic acid

39
Q

18 carbon atoms

A

Stearic acid

40
Q

20 carbon atoms

A

Arachidic acid

Biochem Prelim 2nd Sem (13 decks)

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