Limbic system Flashcards
Papez circuit
Subiculum => mammillary body => anterior thalamic nucleus => cingulate gyrus => entorhinal cortex => hippocampus
Cholinergic neurons from which structures travel back through the fornix to the hippocampus?
Medial septal nuclei & diagonal band of Broca
Kluver Bucy syndrome
Behavioral disturbance following B anterior lobe ablation in monkeys; characterized by hyperorality, loss of normal fear, visual agnosia, placidity, hypersexuality, & hyperphagia
Functions of the limbic system
HOME: homeostasis, olfaction, memory, emotion
3 parts of the hippocampal formation
Dentate gyrus, hippocampus, subiculum
Limbic cortex includes
Parahippocampal gyrus, cingulate gyrus, medial orbitofrontal cortex, temporal pole, anterior insula
Nucleus basalis of Meynert
Part of the basal forebrain; contains cholinergic neurons & is major site of degeneration in AD
3 main nuclei of the amygdala
1) Corticomedial - involved in olfaction/appetitive states 2) Basolateral - direct & indirect connections to diverse cortical areas, basal forebrain, medial thalamus 3) Central nucleus - connects w/ hypothalamus & brainstem, important in autonomic control
The amygdala plays a crucial role in modulating neural impact of sensory stimuli on each of which 3 factors?
Hedonistic value, acquired associations, motivational state
Hippocampal lesions result in
Dissociation between explicit learning of new experience and implicit-procedural learning
Functions of the amygdala
Functions in emotional, autonomic, & neuroendocrine circuits of the limbic system
Entorhinal cortex
Serves as major input & output relay between association cortex & hippocampal formation
3 main targets of axons travelling through the fornix
Medial & lateral mammillary nuclei, lateral septal nucleus, anterior thalamic nucleus
Piriform cortex
Primary olfactory cortex; interconnected with the hypothalamus
Seizures involving the amygdala & adjacent cortex lead to
Emotions of fear & panic
