Leukocytes Flashcards
Where is are WBC and Thrombocytes found
Buffy coat
What are the 2 types of WBC
- Granulocytes - Contains granules in the cytoplasm
- Agranulocytes - No granules in cytoplasm
What are the different types of Granulocytes
- Neutrophils
- Eosinophils
- Basophil
What are the 2 types of Agranuloctyes
- Lymphocytes
- Monocytes
What are some WBC characteristics
Amoeboid movement: Move cytoplasm in the direction of movement
Diapedesis - Cell flattens and leaves vessels
Chemotaxis- Cell attracted by inflammatory chemicals
Pus - Dead WBC at the site of
Neutrophil - % of Neutrophil in circulation, what type of WBC, and function
60%-70% of WBC in circulation
- MOST ABUNDANT
- Granulocyte -3 Lobated nuclei
- First responders to leave circulation, secrete enzymes (Lysosomes) that kill bacteria
- Numbers of Neutrophils increase during bacterial infections
Eosinophil - % of Eosinophil in circulation, what type of WBC, and function
2%-4% of WBC in circulation
- RED Granulocyte/ Lobated nuclei - 2 lobes
- Eosinophils elevated during allergic and inflammatory reaction
- Eosinophils secrete anti-inflammatory chemicals: Anti-histamine
Basophil - % of Basophil in circulation, what type of WBC, and function
0.5 - 1% Circulating WBC
- LEAST ABUNDANT
- Granulocyte/ Blue stain
- Numbers increased in allergic and inflammatory reaction
- Release inflammatory chemicals (Histamine, Heparin)
Lymphocyte - % of Lymphocyte in circulation, what type of WBC, and function
20-25% of WBC in circulation
- Agranulocyte
- Found in lymphatic tissue
- Involved in antibody production, attacking abnormal and viral infections
Monocytes - % of Monocytes in circulation, what type of WBC, and function
3-8% of WBC circulating
- Largest WBC - Agranuloctye
-Remain in circulation for 3 days, then become tissue macrophages
- Numbers increase during prolonged infection
What is a platelet composed of and what is its function
- Platelets are not cells, they are cytoplasmic
pieces from megakaryocytes found in the red bone marrow and are secreted into circulation - Function: Platelet plug