Lesson 3a: Genus actinobacteria

Question 1

trueperrela pyogenes produce ______ a haemolytic exotoxin which is a cytolytic for several cell type including neutrophils & macrophages & is dermonecrotic & lethal for laboratory animals

Answer 1

Pyolisin

Question 2

T. pyogenes also produces adhesin such as ______ & other extracellular matrix-binding proteins & fimbriae, that assist in adherence of the organism to host tissues probably by exposing hidden host cell receptors for other adhesins

Answer 2

neuraminidase

Question 3

because species identification is difficult for organism this _____ is used for confirmation od identity.

Answer 3

PCR analysis of the 16s rRNA

Question 4

this ____ is used for the isolation of T. pyogenes

Answer 4

Loeffler’s a serum slope

Question 5

an opportunistic pathogen & is a common cause of suppurative lesions in many domestic species worldwide, esp in cattle, pigs & sheep

Answer 5

Trueperella pyogenes

Question 6

usual cases of tueperella pyogenes

Answer 6

1. lymphadenitis
2. osteomyelitis
3. peritonitis
4. neural abscessation
5. pyometra
6. metritis
7. acute mastitis in cow

Question 7

dx of t. pyogenes

Answer 7

1. gram staining
2. isolation from cell culture or pitting of Loeffler’s serum slope

Question 8

tx of t. pyogenes

Answer 8

macrolides & tetracyclines

Question 9

this is caused by Actinomyces viscosus that result to subcutaneous pyogranulomatous lesions & extensive fibrovascular proliferation on the peritoneal or pleural surface sanguinopurulent exudate in the affected cavity. The thoracic lesions closely resemble those of canine nocardiosis

Answer 9

Canine actinomycosis

Question 10

The main clinical finding of canine actinomycosis is:

Answer 10

Respiratory distress

Question 11

tx of actinomycosis :

Answer 11

penicillin

Question 12

Bovine actinomycosis or lumpy jaw is caused by?

Answer 12

Actinomyces bovis

Question 13

Actinomyces bovis which result to chronic rarefying osteomyelitis following trauma to the mucosa from rough feed or through dental alveoli during tooth eruption.

Answer 13

Bovine actinomycosis

Question 14

Dx of bovine actinomycosis ;

Answer 14

1. clinical signs
2. radiography

Question 15

Tx of bovine actinomycosis:

Answer 15

1. surgery
2. penicillin,
3. ison

Question 16

This specific disease, which affects the urinary tract of pregnant sows, is transmitted at coitus and fatal.

Answer 16

Porcine cystitis and pyelonephritis

Question 17

the pathogen of porcine cystitis and pyelonephritis can be isolated from the prepuce and preputial diverticulum of healthy boars but not from the urogenital tract of healthy sows.

Answer 17

Actinobaculum suis

Question 18

In Porcine cystitis and pyelonephritis boars are rarely affected clinically and sows usually develop evidence of disease after how many weeks?

Answer 18

3 to 4 weeks after

Question 19

what are the prominent signs of porcine cystitis & pyelonephritis ?

Answer 19

1. Anorexia
2. arching of the back
3. dysuria
4. haematuri

Question 20

If both kidneys are extensively damaged in porcine cystitis & pyelonephritis _____ may occur.

Answer 20

Death