Lesson 3a: Genus actinobacteria Flashcards
trueperrela pyogenes produce ______ a haemolytic exotoxin which is a cytolytic for several cell type including neutrophils & macrophages & is dermonecrotic & lethal for laboratory animals
Pyolisin
T. pyogenes also produces adhesin such as ______ & other extracellular matrix-binding proteins & fimbriae, that assist in adherence of the organism to host tissues probably by exposing hidden host cell receptors for other adhesins
neuraminidase
because species identification is difficult for organism this _____ is used for confirmation od identity.
PCR analysis of the 16s rRNA
this ____ is used for the isolation of T. pyogenes
Loeffler’s a serum slope
an opportunistic pathogen & is a common cause of suppurative lesions in many domestic species worldwide, esp in cattle, pigs & sheep
Trueperella pyogenes
usual cases of tueperella pyogenes
- lymphadenitis
- osteomyelitis
- peritonitis
- neural abscessation
- pyometra
- metritis
- acute mastitis in cow
dx of t. pyogenes
- gram staining
- isolation from cell culture or pitting of Loeffler’s serum slope
tx of t. pyogenes
macrolides & tetracyclines
this is caused by Actinomyces viscosus that result to subcutaneous pyogranulomatous lesions & extensive fibrovascular proliferation on the peritoneal or pleural surface sanguinopurulent exudate in the affected cavity. The thoracic lesions closely resemble those of canine nocardiosis
Canine actinomycosis
The main clinical finding of canine actinomycosis is:
Respiratory distress
tx of actinomycosis :
penicillin
Bovine actinomycosis or lumpy jaw is caused by?
Actinomyces bovis
Actinomyces bovis which result to chronic rarefying osteomyelitis following trauma to the mucosa from rough feed or through dental alveoli during tooth eruption.
Bovine actinomycosis
Dx of bovine actinomycosis ;
- clinical signs
- radiography
Tx of bovine actinomycosis:
- surgery
- penicillin,
- ison
This specific disease, which affects the urinary tract of pregnant sows, is transmitted at coitus and fatal.
Porcine cystitis and pyelonephritis
the pathogen of porcine cystitis and pyelonephritis can be isolated from the prepuce and preputial diverticulum of healthy boars but not from the urogenital tract of healthy sows.
Actinobaculum suis
In Porcine cystitis and pyelonephritis boars are rarely affected clinically and sows usually develop evidence of disease after how many weeks?
3 to 4 weeks after
what are the prominent signs of porcine cystitis & pyelonephritis ?
- Anorexia
- arching of the back
- dysuria
- haematuri
If both kidneys are extensively damaged in porcine cystitis & pyelonephritis _____ may occur.
Death
