Lesson 3.5 Flashcards
New agent for treating hypertensive emergencies
FENOLDOPAM
This medication has potent vasodilatory effects through stimulation of the dopamine-1 receptor.
FENOLDOPAM
Vasovagal reactions, hypotension, hypertension, syncope, tachycardia, pallor, chest pain, and cardiac arrest.
CARDIOVASCULAR EVENTS
General gastric pain, nausea, vomiting, sialorrhea (excessive salivation), xerostomia (too little salivation), and dysgeusia (bad taste in mouth).
GASTROINTESTINAL ADVERSE EFFECTS
Include nausea, vomiting, flushing with a generalized feeling of warmth, rhinitis, lacrimation, sneezing, itching, rash, angioedema, generalized edema, cramps, excessive salivation, salivary gland swelling, diaphoresis, retching and choking, metallic taste in mouth, decreased white blood cells, chills, fever, and disseminated intravascular coagulation (DIC).
GENERAL ADVERSE REACTIONS
Dizziness, paresthesias, drowsiness, weakness, thirst, headache, and seizures.
CNS ADVERSE EFFECTS
ROCM are responsible for approximately 10% of all acute renal failure (ARF) events and are the third most common cause of hospital-acquired ARF.
RENAL DYSFUNCTION
Adverse effects that may be seen after the use of the ferumoxide compounds (iron compounds), such as ferumoxtran-10 (Combidex), iron oxide (Clariscan), and ferumoxytol, include hypotension if infused too rapidly; it is recommended not to exceed 25 to 30 ml/hr.
FERUMOXIDE COMPOUNDS
Occurs in patients who have decompensated thyrotoxicosis, a condition in which the body becomes unable to tolerate thyroid hormones.
THYROID STORM
Signs and symptoms of thyroid storm include fever, tachycardia (rapid heart rate), diaphoresis (sweating), agitation, nervousness, and emotional instability
THYROID STORM
A life-threatening, systemic hypersensitivity reaction.
ANAPHYLAXIS (type I hypersensitivity reaction)
Patients suffering anaphylaxis may exhibit any combination of nausea, vomiting, diarrhea, hives, rash, flushing, cyanosis, pallor, lightheadedness, unconsciousness, seizures, stridor, wheezing, respiratory distress, bronchospasm, & etc.
ANAPHYLAXIS (type I hypersensitivity reaction)
A heart rhythm disturbance characterized by electrical impulses without cardiac contraction. The heart monitor shows electrical activity, but the heart is not pumping.
PULSELESS ELECTRICAL ACTIVITY (PEA)
The heart has ceased to pump blood effectively to maintain life
CARDIAC ARREST
Diagnostic effects of intravascular radiopaque contrast media (ROCM) are a function of the iodine contained within them. Adverse effects elicited by ROCM depend at least partially on their serum or tissue iodine concentration and osmolality and their calcium-chelating, anticoagulant, and immune system-stimulating abilities.
IODINATED RADIOPAQUE CM
