Lesson 2.3 Flashcards
Jaundice is not a disease but rather
a sign of one of the many possible underling pathological processes the may occur
jaundice aka
icterus
jaundices signs
yellowish pigmentation of skin, white of eyes and other mucous membranes
what is jaudice caused by
hyperbilirubinemia
what Is hyperbilirubinemia
increased levels of bilirubin in the blood and extracellular fluid
what is bilirubin usually excreted in
bile and ruin
causes of jaundice/hyperbillirubinemia (3)
liver disease (ex. hepatitis and cirrhosis) liver or pancreatic cancer obstruction of biliary tract
normal total bilirubin
0.3-1.1 d/L
normal direct bilirubin
0.1-0.4 d/L
bilirubin is product from
the breakdown of hemoglobin in old red blood cells
what gives skin yellow colour
leakage of bilirubin into the tissues
bilirubin reflects
the balance between the production and excretion of bile
elevation of direct/conjugative bilirubin is associated with
obstruction, hepatitis, cirrhosis and liver mets
elevation of indirect/unconjugative bilirubin is associated with
non obstructive conditions like steatosis
symptoms of jaundice (5)
pruritis (itchyness) fatigue abdo pain weight loss vomiting